Lindahl Lab

2018-2021

“The Pyrococcus furiosus ironome is dominated by [Fe4S4]2+ clusters or thioferrate-like iron depending on the availability of elemental sulfur”Shaik Waseem Vali, Dominik K. Haja, Richard A. Brand, Michael W. W. Adams, and Paul A. Lindahl. Journal of Biological Chemistry (2021) 296, article 100710, pp. 1-15.

“Low‑molecular‑mass labile metal pools in Escherichia coli: advances using chromatography and mass spectrometry”Hayley N. Brawley and Paul A. Lindahl (2021) Journal of Biological Inorganic Chemistry 26, 479–494.

“Mössbauer and LC-ICP-MS investigation of iron trafficking between vacuoles and mitochondria in Vma2Δ Saccharomyces cerevisiae”Joshua E. Kim, Shaik Waseem Vali, Trang Q. Nguyen, Andrew Dancis, and Paul A. Lindahl (2021) Journal of Biological Chemistry Article number 100141, https://doi.org/10.1074/jbc.RA120.015907. Pp. 1-14.

“A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins”Danish Khan, Dongju Lee, Gulcin Gulten, Anup Aggarwal, Joshua J. Wofford, Inna Krieger, Ashutosh Tripathi, John W. Patrick, Debra M. Eckert, Arthur A Laganowsky, James Sacchettini, Paul A. Lindahl, Vytas A. Bankaitis, (2020) ELIFE 9, Article Number: e57081. DOI: 10.7554/eLife.57081

“Chromatographic detection of low-molecular-mass metal complexes in the cytosol of Saccharomyces cerevisiae”Trang Q Nguyen, Joshua E Kim, Hayley N. Brawley, and Paul A. Lindahl (2020) Metallomics, 12, 1094-1105. DOI: 10.1039/c9mt00312f

“Acetyl-coenzyme A synthase: a beautiful metalloenzyme”Paul A. Lindahl in “Bioorganometallic Chemistry” (Ulf-Peter Apfel and Wolfgang Weigand, Editors). De Gruyter, Berlin, Germany. 2020, Chapter 7, pp 279-312. DOI: 10.1515/9783110496574-007

“COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase”Shivatheja Soma, Marcos N Morgada, Mandar T. Naik, Aren Boulet, Anna A Roesler, Nathaniel Dziuba, Alok Ghosh, Qinhong Yu, Paul A. Lindahl, James B Ames, Scot C. Leary, Alejandro J. Vila, and Vishal M. Gohil (2019) Cell Reports 29, 4114-4126. DOI: 10.1016/j.celrep.2019.11.054

“The thermally induced decarboxylation mechanism of a mixed-oxidation state carboxylate-based iron metal-organic framework”Hannah. F. Drake, Gregory S. Day, Shaik W. Vali, Zhifeng Xiao, Sayan Banerjee, Jialuo Li, Elisabeth A. Joseph, Jason E. Kuszynski, Zachary T. Perry, Angelo Kirchon, Osman K. Ozdemir, Paul A. Lindahl, and Hong-Cai Zhou (2019) Chemical Communications. 55, 12769-12772.

“Low-molecular-mass iron complexes in blood plasma of iron-deficient pigs do not originate directly from nutrient iron”Nathanial Dziuba, Joanne Hardy, and Paul A. Lindahl (2019) Metallomics, 11. DOI: 10.1039/c9mt00152b

“A comprehensive mechanistic model of iron metabolism in Saccharomyces cerevisiae”Paul A. Lindahl, Metallomics, 2019 11, 1779-1799

“COA6 is structurally tuned to function as a thiol-disulfide oxidoreductase in copper delivery to mitochondrial cytochrome c oxidase”Shivatheja Soma, Marcos N. Morgada, Mandar T. Naik, Aren Boulet, Anna A. Roesler, Nathaniel Dziuba, Alok Ghosh, Qinhong Yu, Paul A. Lindahl, James B. Ames, Scot C. Leary, Alejandro J. Vila, and Vishal M. Gohil. Cell Reports, 2019, 29, 4114-4126.e5

“Isolated Saccharomyces cerevisiae Vacuoles contain Low-Molecular-Mass Transition-Metal Polyphosphate Complexes”Trang Q. Nguyen, Nathaniel Dziuba, and Paul A. Lindahl (2019) Metallomics. DOI: 10.1039/c9mt00104b

“A mathematical model of iron import and trafficking in wild-type and Mrs3/4ΔΔ yeast Cells”Joshua D. Wofford and Paul A. Lindahl (2019) BMC Systems Biology 13: Article number 23. DOI: 10.1186/s12918-019-0702-2

“Evidence that a respiratory shield in Escherichia coli protects a low molecular mass FeII pool from O2-dependent oxidation”Joshua D. Wofford, Naimah Bolaji, Nathaniel Dziuba, F. Wayne Outten, and Paul A. Lindahl (2019) J. Biol. Chem., 294, 50-62. DOI: 10.1074/jbc.RA118.005233

“Low-molecular-mass iron in healthy blood plasma is not predominately ferric citrate”Nathaniel Dziuba, Joanne Hardy, and Paul A. Lindahl (2018) Metallomics, 10, 802-817

“Mitochondria Export Sulfur Species Required for Cytosolic tRNA Thiolation”Alok Pandey, Jayashree Pain, Nathaniel Dziuba, Ashutosh K. Pandey, Andrew Dancis, Paul A. Lindahl, and Debkumar Pain (2018) Cell Chemical Biology 25, 738-748

“Recovery of mrs3ΔmrsΔ Saccharomyces cervisiae cells under Iron-Sufficient Conditions, and the Role of Fe580.”Michael J. Moore, Joshua D. Wofford, Andrew Dancis, and Paul A. Lindahl, 2018, Biochemistry, 57, 672-683

2015-2017

“Mossbauer Spectra of Mouse Hearts reveal age-dependent changes in mitochondrial and ferritin iron levels.”Joshua D. Wofford, Mrinmoy Chakrabarti, and Paul A. Lindahl, 2017, Journal of Biological Chemistry, 13, 5546-5554

“Ferric ions accumulate in the walls of metabolically inactivating Saccaromyces cerevisiae cells and are reductively mobilized during reactivation.”Joshua D. Wofford, Jinkyu Park, Sean P. McCormick, Mrinmoy Chakrabarti, and Paul A. Lindahl, 2015, Metallomics, 7, 692-708

“Labile Low-Molecular-Mass Complexes in Mitochondria: Trials and Tribulations of a Burgeoning Field.”Paul A. Lindahl and Michael J. Moore, 2016, Biochemistry, 30, 4140-4153

“Speciation of iron in mouse liver during development, iron deficiency, IRP2 deletion and inflammatory hepatitis.”Mrinmoy Chakrabarti, Allison L. Cockrell, Jinkyu Park, Sean P. McCormick, Lora S. Lindahl, and Paul A. Lindahl, 2015, Metallomics, 1, 520-529

“Detection of Labile Low-Molecular Mass Transition Metal Complexes in Mitochondria.”Sean P. McCormick, Michael J. Moore, and Paul A. Lindahl, 2015, Biochemistry, 22, 3442-3453

“Kinetics of iron import into developing mouse organs determined by a pup-swapping method.”Mrinmoy Charkrabarti, Mirza Nofil Barlas, Sean P. McCormick, Lora S. Lindahl, and Paul A. Lindahl, 2015, Journal of Biological Chemistry, 1, 520-528

“Mitochondrial iron-sulfur cluster activity and cytosolic iron regulate iron traffic in Saccaromyces cerevisiae.”Joshua D. Wofford, Paul A. Lindahl, 2015, Journal of Biological Chemistry, 45, 29698-26977

2012-2014

“The Lack of Synchronization between Iron Uptake and Cell Growth Leads to Iron Overload in Saccharomyces cerevisiae during Post-exponential Growth Modes.” Jinkyu Park, Sean P. McCormick, Mrinmoy Chakrabarti, and Paul A. Lindahl. Biochemistry, 2013. online.

“Mössbauer Study and Modeling of Iron Import and Trafficking in Human Jurkat Cells.” Nema D. Jhurry, Mrinmoy Chakrabarti, Sean P. McCormick, Vishal M. Gohil, and Paul A. Lindahl, 2013, Biochemistry 52: 7926-7942.

“Insights into the iron-ome and manganese-ome of Δmtm1 Saccharomyces cerevisiae mitochondria.”Jinkyu Park, Sean P. McCormick, Mrinmoy Chakrabarti and Paul A. Lindahl, 2013, Metallomics. 5: 656-672.

“Low-molecular-mass metal complexes in the mouse brain.” Sean P. McCormick, Mrinmoy Chakrabarti, Allison L. Cockrell, Jinkyu Park, Lora S. Lindahl and Paul A. Lindahl, 2013, Metallomics 5: 232-241.

“Iron Content of Saccharomyces cerevisiae Cells Grown under Iron-Deficient and Iron-Overload Conditions.” Gregory P.Holmes-Hampton, Nema D. Jhurry, Sean P. McCormick, and Paul A. Lindahl, 2012, Biochemistry 52: 105-114.

“Changing iron content of the mouse brain during development.” Gregory P. Holmes-Hampton, Mrinmoy Chakrabarti, Allison L. Cockrell, Sean P. McCormick, Louise C. Abbott, Lora S. Lindahl, and Paul A. Lindahl, 2012. Metallomics 4: 761-770.

“Biophysical Investigation of the Ironome of Human Jurkat Cells and Mitochondria.” Nema D. Jhurry, Mrinmoy Chakrabarti, Sean P. McCormick, Gregory P. Holmes-Hampton, Paul A. Lindahl, 2012, Biochemistry 51: 5276-84.

“Mixed-Valence Nickel-Iron Dithiolate Models of the [NiFe]-Hydrogenase Active Site” David Schilter, Mark J. Nilges, Mrinmoy Chakrabarti, Paul A. Lindahl, Thomas B. Rauchfuss and Matthias Stein, 2012, Inorg Chem 51: 2338-48.

“Metal-metal bonds in biology” Paul A. Lindahl, 2012, J Inorg Biochem 106: 172-8.

2006-2011

“Mössbauer and EPR study of iron in vacuoles from fermenting Saccharomyces cerevisiae” Allison L. Cockrell, Gregory P. Holmes-Hampton, Sean P. McCormick, Mrinmoy Chakrabarti and Paul A. Lindahl, 2011, Biochemistry 50: 10275-83.

“The catalase activity of diiron adenine deaminase” Siddhesh S. Kamat, Gregory P. Holmes-Hampton, Ashima Bagaria, Desigan Kumaran, Shane E. Tichy, Tarun Gheyi, Xiaojing Zheng, Kevin Bain, Chris Groshong, Spencer Emtage, J. Michael Sauder, Stephen K. Burley, Subramanyam Swaminathan, Paul A. Lindahl, Frank M. Raushel, 2011, Protein Sci 20: 2080-94.

“Catalytic mechanism and three-dimensional structure of adenine deaminase” Siddhesh S. Kamat, Ashima Bagaria, Desigan Kumaran, Gregory P. Holmes-Hampton, Hao Fan, Andrej Sali, J. Michael Sauder, Stephen K. Burley, Paul A. Lindahl, Subramanyam Swaminathan and Frank M. Raushel, 2011, Biochemistry 50: 1917-27.

“Biophysical Probes of Iron Metabolism in Cells and Organelles” Paul A. Lindahl and Gregory P. Holmes-Hampton, Current Opinion in Chemical Biology, 2011, 15: 342-6.

“Mathematical Model of a Cell Size Checkpoint” Marco Vilela, Jeffrey J. Morgan, and Paul A. Lindahl 2010, PloS Computational Biology 6(12) 1-11.

“Biophysical Characterization of Iron in Mitochondria Isolated from Respiring and Fermenting Yeast”Jessica Garber-Morales, Gregory P. Holmes-Hampton, Ren Miao, Yisong Guo, Eckard Münck, and Paul A. Lindahl 2010 Biochemistry, 49, 5436-5444

“A Nonheme High-Spin Ferrous Pool in Mitochondria Isolated from Fermenting Saccharomyces cerevisiae” Gregory P. Holmes-Hampton, Ren Miao, Jessica Garber-Morales, Yisong Guo, Eckard Münck, and Paul A. Lindahl 2010 Biochemistry, 49, 4227-4234.

“Biophysical Characterization of the Iron in Mitochondria from Atm1p-Depleted Saccharomyces cerevisiae” Ren Miao, Hansoo Kim, Uma Mahendra Kumar Koppolu, E. Ann Ellis, Robert A. Scott, and Paul A. Lindahl 2009 Biochemistry 48, 9556-9568.

“Mathematical modeling of a minimal protocell with coordinated growth and division” Ivan V. Surovtsev, Zhigang Zhang, Paul A. Lindahl, and Jeffrey J. Morgan 2009, Journal of Theoretical Biology 260, 422-429.

“Novel domain arrangement in the crystal structure of a truncated acetyl-CoA synthase from Moorella thermoacetica” Anne Volbeda, Claudine Darnault, Xiangshi Tan, Paul A. Lindahl and Juan C. Fontecilla-Camps 2009, Biochemistry, 48, 7916-7926.

“Isolation of Saccharomyces cerevisiae Mitochondria for Mössbauer, EPR and Electronic Absorption Spectroscopic Analyses” Paul A. Lindahl, Jessica Garber Morales, Ren Miao, and Gregory Holmes-Hampton, 2009; Methods in Enzymology, Vol. 456, Ch. 15, 268-286.

“EPR and Mössbauer Spectroscopy of Intact Mitochondria Isolated from Yah1p-depleted Saccharomyces cerevisiae” Ren Miao, Marlène Martinho, Jessica Garber Morales, Hansoo Kim, E. Ann Ellis, Roland Lill, Michael P. Hendrich, Eckard Münck and Paul A. Lindahl, 2008 Biochemistry, 47, 9888-9899.

“Kinetic Modeling of the Assembly, Dynamic Steady State, and Contraction of the FtsZ Ring in Prokaryotic Cytokinesis” Ivan V. Surovtsev, Jeffrey J. Morgan, Paul A. Lindahl, 2008 Plos Computational Biology, 4, 1-19.

“Nickel-Carbon Bonds in Acetyl-Coenzyme A synthases/carbon monoxide dehydrogenases” (2008) Paul A. Lindahl, in Vol. 6 of 'Metal Ions in Life Sciences'; A. Sigel, H. Sigel, R. K. O. Sigel, Eds.; John Wiley & Sons, Ltd., Chichester, UK, in press.

“Mössbauer Evidence for an Exchange-Coupled {[Fe4S4]1+:Nip1+} A-cluster in Isolated Alpha Subunits of Acetyl-Coenzyme A Synthase/Carbon Monoxide Dehydrogenase” Xiangshi Tan, Marlène Martinho, Audria Stubna, Paul A. Lindahl, and Eckard Münck, 2008 J. Am. Chem. Soc. 130, 6712-6713.

"Tunnel Mutagenesis and Ni-dependent Reduction and Methylation of the Alpha Subunit of Acetyl-Coenzyme A Synthase/Carbon Monoxide Dehydrogenase" Xiangshi Tan and Paul A. Lindahl, 2008, J. Biol. Inorg. Chem. 13, 771-778.

“Implications of a Carboxylate-Bound C-Cluster Structure of Carbon Monoxide Dehydrogenase” Paul A. Lindahl, 2008, Angew. Chem. Int. Ed., 47, 2–5

“Nickel-dependent oligomerization of the alpha subunit of acetyl-coenzyme a synthase/carbon monoxide dehydrogenase” Xiangshi Tan, Ioannis Kagiampakis, Ivan Surovtsev, Borries Demeler and Paul A. Lindahl, 2007, Biochemistry 46, 11606-11613

“Electron paramagnetic resonance and Mössbauer spectroscopy of intact mitochondria from respiring Saccharomyces cerevisiae ” Brandon N. Hudder, Jessica Garber Morales, Audria A. Stubna, Eckard Münck, Michael P. Hendrich, and Paul A. Lindahl, 2007, J. Biol. Inorg. Chem. 12, 1029-1053.

“Acetyl-Coenzyme A synthases and Nickel-containing carbon monoxide dehydrogenases” (2007) Paul A. Lindahl, and David E. Graham, in "Nickel and Its Surprising Impact in Nature", Vol. 2 of 'Metal Ions in Life Sciences'; A. Sigel, H. Sigel, R. K. O. Sigel, Eds.; John Wiley & Sons, Ltd., Chichester, UK, 2, 357-416.

“Whole-cell modeling framework in which biochemical dynamics impact aspects of cellular geometry” Ivan V Surovtsev, Jeffrey J Morgan and Paul A Lindahl, Journal of Theoretical Biology, 2007, 244, 154-166.

“Kinetics of CO Insertion and Acetyl Group Transfer Steps, and a Model of the Acetyl- CoA Synthase Catalytic Mechanism” Xiangshi Tan, Ivan V. Surovtsev and Paul A. Lindahl Journal of the American Chemical Society 2006, 128, 12331-12338.

“Mössbauer and EPR Study of Recombinant Acetyl-CoA Synthase from Moorella thermoacetica” Matthew R. Bramlett, Audria Stubna, Xiangshi Tan, Ivan V. Surovtsev, Eckard Münck and Paul A. Lindahl, Biochemistry, 2006, 45, 8674-8685.

“Function of the Tunnel in Acetyl-Coenzyme A Synthase/Carbon Monoxide Dehydrogenase” Xiangshi Tan, Anne Volbeda, Juan C. Fontecilla-Camps, and Paul A. Lindahl, Journal of Biological Inorganic Chemistry, 2006, 11, 371-378.

2000-2005

“The tunnel of acetyl-Coenzyme A synthase/carbon monoxide dehydrogenase regulates delivery of CO to the active site” Xiangshi Tan, Huay-Keng Loke, Shawn Fitch and Paul A. Lindahl, Journal of the American Chemical Society 2005, 127, 5833-5839.

“LdpA: a component of the circadian clock senses redox state of the cell” Natalia B. Ivleva, Matthew R. Bramlett, Paul A. Lindahl, and Susan S. Golden, The EMBO Journal, 2005, 24, 1202-1210

“A Framework for Whole-Cell Mathematical Modeling” Jeffrey J. Morgan, Ivan V. Surovtsev, and Paul A. Lindahl, Journal of Theoretical Biology 2004, 231, 581-596.

“Acetyl-Coenzyme A Synthase: The Case for a Nip0-Based Mechanism of Catalysis” Paul A. Lindahl, J. Biol. Inorg. Chem. 2004 ,9, 516-524.

“Effect of Sodium Sulfide on Ni-Containing Carbon Monoxide Dehydrogenases" Jian Feng and Paul A. Lindahl, J. Am. Chem. Soc. 2004, 126, 9094-9100.

“Stepwise Evolution of Nonliving to Living Chemical Systems”Paul A. Lindahl, Origins of Life and Evolution of the Biosphere, 2004, 34, 371-389.

“Evidence for a Proton Transfer Network and a Required Persulfide-Bond-Forming Cysteine Residue in Ni-Containing Carbon Monoxide Dehydrogenases” Eun Jin Kim, Jian Feng, Matthew R. Bramlett, and Paul A. Lindahl, Biochemistry 2004, 43, 5728-5734.

“Effect of Zn on Acetyl Coenzyme A Synthase: Evidence for a Conformational Change in the Alpha Subunit During Catalysis”, Xiangshi Tan, Matthew R. Bramlett and Paul A. Lindahl, J. Am. Chem. Soc. 2004, 126, 5954-5955.

“Autocatalytic activation of acetyl-CoA synthase” Ernest L. Maynard, Xiangshi Tan, and Paul A. Lindahl, J. Biol. Inorg. Chem. 2004, 9, 316-322.

“Structures and energetics of models for the active site of acetyl-coenzyme a synthase: Role of distal and proximal metals in catalysis” Charles E. Webster, Marcetta Y. Darensbourg, Paul A. Lindahl, and Michael B. Hall, J. Am. Chem. Soc., 2004, 126, 3410-3411.

“Carbon Monoxide Dehydrogenase from Rhodospirillum rubrum: Effect of Redox Potential on Catalysis” Jian Feng and Paul A. Lindahl, Biochemistry, 2004, 43, 1552-1559.

“Inactivation of Acetyl-CoA Synthase/Carbon Monoxide Dehydrogenase by Copper” Matthew R. Bramlett, Xiangshi Tan, and Paul A. Lindahl, J. Am. Chem. Soc., 2003, 125, 9316- 9317.

“Ni-Zn-[Fe4S4] and Ni-Ni-[Fe4S4] Clusters in Closed and Open Subunits of Acetyl-CoA Synthase/Carbon Monoxide Dehydrogenase” Claudine Darnault, Anne Volbeda, Eun Jin Kim, P. Legrand, Xavier Vernede, Paul A. Lindahl, and Juan C. Fontecilla-Camps, Nature Structural Biology, 2003, 10, 271-279.

“Evaluation of Multivalent Dendrimers Based on Melamine: Kinetics of Thiol-Disulfide Exchange Depends on the Structure of the Dendrimer” W. Zhang, S.E. Tichy, Lisa M. Perez, Gheorghe C. Maria, Paul A. Lindahl, and Eric E. Simanek, J. Am. Chem. Soc., 2003, 125, 5086- 5094.

“Dynamic Responses of Protein Homeostatic Regulatory Mechanisms to Perturbations from Steady State”, Qingwu Yang, Paul A. Lindahl and Jeffrey J. Morgan, Journal of Theoretical Biology, 2003, 222, 407-423.

“Identification and preliminary characterization of acsF, a Putative Ni-insertase used in the biosynthesis of acetyl-CoA synthase from Clostridium thermoaceticum ” Huay-Keng Loke and Paul A. Lindahl, Journal of Inorganic Biochemistry, 2002, 93, 33-40.

“Reduction and Methyl Transfer Kinetics of the Alpha Subunit from Acetyl-Coenzyme A Synthase” Xiangshi Tan, Christopher Sewell, Qingwu Yang, and Paul A. Lindahl, J. Am. Chem. Soc. 2003, 125, 318-319.

“Stoichiometric Redox Titrations of Complex Metalloenzymes” Paul A. Lindahl, Methods in Enzymology, 2002, 354, 296-309.

“Genetic Construction of Truncated and Chimeric Metalloproteins Derived from the Alpha Subunit of Acetyl-CoA Synthase from Clostridium thermoaceticum ” Huay-Keng Loke, Xiangshi Tan, and Paul A. Lindahl, J. Am. Chem. Soc., 2002, 124, 8667-8672.

“Analysis of Protein Homeostatic Regulatory Mechanisms in Perturbed Environments at Steady-State”, Christopher Sewell, Jeffrey J. Morgan, and Paul A. Lindahl, Journal of Theoretical Biology, 2002, 215, 151-167.

“Stopped-Flow Kinetics of Methyl Group Transfer between the Corrinoid-Iron-Sulfur Protein and Acetyl-Coenzyme A Synthase from Clostridium thermoaceticum ”, Xiang Shi Tan, Christopher Sewell and Paul A. Lindahl, J. Am. Chem. Soc., 2002, 124, 6277-6284.

“Carbon Monoxide Dehydrogenases and Acetyl-CoA Synthases: Light at the End of the Tunnel?” Paul A. Lindahl, Biochemistry 2002, 41, 2097-2105.

“Catalytic Coupling of the Active Site in Acetyl-CoA Synthase, a Bifunctional CO- Channeling Enzyme” Ernest L. Maynard and Paul A. Lindahl Biochemistry, 2001, 40, 13262- 13267. (Designated a “hot article” by the editors of Biochemistry)

“The Evolution of Acetyl-CoA Synthase” Paul A. Lindahl and Belinda Chang, Origins of Life and Evolution of the Biosphere, 2001, 31, 403-434

“Kinetic Mechanism of Acetyl-CoA Synthase: Steady-State Synthesis at Variable CO/CO2 Pressures” Ernest L. Maynard, Christopher Sewell, and Paul A. Lindahl, J. Am. Chem. Soc., 2001, 123, 4697-4703.

1994-1999

"2,4,6-Trinitrotoluene (TNT) Reduction by Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum " Shouqin Huang, Paul A. Lindahl, Chuanyue Wang, George N. Bennett, Fredrick B. Rudolf, and Joseph B. Hughes, Applied and Environmental Microbiology, 2000 66, 1474-1478.

“Active Acetyl-CoA Synthase from Clostridium thermoaceticum obtained by Cloning and Heterologous Expression of acsAB in Escherichia coli ”, Huay Keng Loke, George Bennett, and Paul A. Lindahl, Proc. Natl. Acad. Sci. USA 2000, 97, 12530-12535.

“Equilibrium Dialysis Study and Mechanistic Implications of Coenzyme A Binding to Acetyl-CoA Synthase/Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum ” Wilson, B. E. and Lindahl, P. A. Journal of Biological Inorganic Chemistry, 1999, 4, 742-748.

“Evidence for a Proposed Intermediate Redox State in the CO/CO2 Active Site of Acetyl-Coenzyme A Synthase (Carbon Monoxide Dehydrogenase) from Clostridium thermoaceticum ” Daniel M. Fraser and P. A. Lindahl Biochemistry, 1999, 38, 15706-15711.

“Stoichiometric CO Reductive Titrations of Acetyl-CoA Synthase (Carbon Monoxide Dehydrogenase) from Clostridium thermoaceticum ” Daniel M. Fraser and Paul A.Lindahl, Biochemistry, 1999, 38, 15697-15705.

“Evidence of a Molecular Tunnel Connecting the Active Sites for CO2 Reduction and Acetyl-CoA Synthesis in Acetyl-CoA Synthase from Clostridium thermoaceticum ” Ernest L. Maynard and Paul A. Lindahl, Journal of the American Chemical Society, 1999, 121 9221-9222.

“Spectroscopic, Redox and Structural Characterization of the Ni-Labile and Nonlabile Forms of the Acetyl-CoA Synthase Active Site of CO Dehydrogenase” William K. Russell, Christina M. V. Stålhandske, Jinqiang Xia, Robert A. Scott, and Paul A. Lindahl, J. Am. Chem. Soc. 1998, 120, 7502-7510.

“CO/CO2 Potentiometric Titrations of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum: Effect of CO2 and Evidence for Redox Cooperativity” William K. Russell and Paul A. Lindahl Biochemistry, 1998, 37, 10016-10026.

"A Multinuclear ENDOR study of the C-cluster in CO Dehydrogenase from Clostridium thermoaceticum: Evidence for HxO and Histidine Coordination to the [Fe4S4] Center" Victoria J. DeRose, Joshua Telser, Mark E. Anderson, Paul A. Lindahl, and Brian M. Hoffman J. Am. Chem. Soc. 1998, 120, 8767-8776.

“Mössbauer and EPR Study of the Ni-Activated α Subunit of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum “ Jinqiang Xia, Zhengguo Hu, Codrina Popescu, Paul A. Lindahl, and Eckard Münck J. Am. Chem. Soc. 1997, 119, 8301-8312.

“Methylation of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum and the Mechanism of Acetyl-CoA Synthesis” David P. Barondeau and Paul A. Lindahl   J. Am. Chem. Soc. 1997, 119, 3959-3970.

“Spectroelectrochemical Characterization of the Metal Centers in Carbon Monoxide Dehydrogenase (CODH) and Nickel-deficient CODH from Rhodospirillum rubrum ” Nathan J. Spangler, Paul A. Lindahl, Vahe Bandarian, and Paul W. Ludden J. Biol. Chem. 1996, 271, 7973 - 7977.

"Spectroscopic States of the CO Oxidation / CO2 Reduction Active Site of Carbon Monoxide Dehydrogenase and Mechanistic Implications" Mark E. Anderson and Paul A. Lindahl Biochemistry. 1996, 35, 8371-8380.

"The Nature of the C-cluster in Ni-Containing Carbon Monoxide Dehydrogenases" Zhengguo Hu, Nathan J. Spangler, Mark E. Anderson, Jinqiang Xia, Paul W. Ludden, Paul A. Lindahl, and Eckard Münck, J. Am. Chem. Soc. 1996, 118, 830-845.

"Assembly of an Exchange-Coupled [Ni : Fe4S4] Cluster in the α Metallosubunit of CO Dehydrogenase from Clostridium thermoaceticum with Spectroscopic Properties and CO- Binding Ability Mimicking the Acetyl-CoA Synthase Active Site" Jinqiang Xia and Paul A. Lindahl. J. Am. Chem. Soc. 1996, 118, 483-484.

"CO Dehydrogenase from Clostridium thermoaceticum: Quaternary Structure and Stoichiometry of its SDS-Induced Dissociation" Jinqiang Xia, James F. Sinclair, Thomas O. Baldwin, and Paul A. Lindahl. Biochemistry 1996, 35, 1965-1971.

"EXAFS, EPR, and Electronic Absorption Spectroscopic Study of the α Metallosubunit of CO Dehydrogenase from Clostridium thermoaceticum " Jinqiang Xia, Jun Dong, Shengke Wang, Robert A. Scott, and Paul A. Lindahl. J. Am. Chem. Soc, 1995, 117, 7065 - 7070.

"Decomposition of Carbon Monoxide Dehydrogenase into α Metallosubunits and a Catalytically-Active Form Consisting Primarily of b Metallosubunits" Jinqiang Xia and Paul A. Lindahl. Biochemistry, 1995, 34, 6037-6042.

"Stoichiometric Reductive Titrations of Desulfovibrio gigas Hydrogenase" Lee Melvin Roberts and Paul A. Lindahl. J. Am. Chem. Soc, 1995, 117, 2565-2572.

"Utilization of Copper as a Paramagnetic Probe for the Binuclear Metal Center of Phosphotriesterase" Myeong Yun Chae, George A. Omburo, Paul A. Lindahl and Frank M. Raushel. Archives of Biochemistry and Biophysics, 1995, 316, 765-772.

1988-1993

"Analysis of Oxidative Titrations of Desulfovibrio gigas Hydrogenase; Implications for the Catalytic Mechanism" Lee Melvin Roberts and Paul A. Lindahl. Biochemistry, 1994, 33, 14339 - 14349.

"Organization of Clusters and Internal Electron Pathways in CO Dehydrogenase from Clostridium thermoaceticum; Relevance to the Mechanism of EPR Study of Cyanide-Inhibited Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum " Mark E. Anderson and Paul A. Lindahl, Biochemistry, 1994, 33, 8702 - 8711.

"Stability of the Ni-C State and Oxidative Titrations of the Nickel Hydrogenase from Desulfovibrio gigas Monitored by EPR and Electronic Absorption Spectroscopies" David P. Barondeau, Lee Melvin Roberts, and Paul A. Lindahl. J. Am. Chem. Soc, 1994, 116, 3442 - 3448.

"Identification of a Cyanide Binding Site of CO Dehydrogenase from Clostridium thermoaceticum using EPR and ENDOR Spectroscopies" Mark E. Anderson, Victoria J. DeRose, Brian M. Hoffman, and Paul A. Lindahl. J. Am. Chem. Soc., 1993, 115, 12204 - 12205.

"Antiferromagnetic Coupling in the Binuclear Metal Cluster of Mn-Substituted Phosphotriesterase" Myeong Yun Chae, George A. Omburo, Paul A. Lindahl, and Frank M. Raushel J. Am. Chem. Soc., 1993, 115, 12173 - 12174.

"Identification of the CO Oxidation Site of CO Dehydrogenase by EPR and ENDOR Studies of the Cyanide-Inhibited State" Mark E. Anderson, Victoria J. DeRose, Brian M. Hoffman, and Paul A. Lindahl J. Inog. Biochem., 1993, 51, 204.

"Oxidative Titrations of Desulfovibrio Gigas Hydrogenase Monitored by EPR and Electronic Absorption Spectroscopies" David Barondeau, Lee Melvin Roberts, and Paul A. Lindahl J. Inog. Biochem., 1993, 51, 53.

"Stability and Redox Potential of Ni-C from Nickel-Iron Hydrogenase" Lee Melvin Roberts, David Barondeau, and Paul A. Lindahl J. Inog. Biochem., 1993, 51, 52.

"Heterogeneous Nickel Environments in Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum " Woonsup Shin, Mark E. Anderson, and Paul A. Lindahl J. Am. Chem. Soc., 1993, 115, 5522 - 5526.

"Effects of Sulfur Site Modification on the Redox Potentials of Derivatives of [N,N'- Bis(2-mercaptoethyl)-1,5,-diazacyclooctanato]nickel(II)" Patrick J. Farmer, Joseph H. Reibenspies, Paul A. Lindahl, and Marcetta Y. Darensbourg J. Am. Chem. Soc., 1993, 115, 4665 - 4674.

"Low Spin Quantitation of NiFeC EPR Signal from Carbon Monoxide Dehydrogenase Is Not Due to Damage Incurred During Protein Purification" Woonsup Shin and Paul A. Lindahl Biochim. Biophys. Acta 1993, 1161, 317 - 322.

"Discovery of a Labile Nickel Ion Required for CO/Acetyl-CoA Exchange Activity in the NiFe Complex of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum," Woonsup Shin and Paul A. Lindahl, J. Am. Chem. Soc. 1992, 114, 9718 - 9719.

"Function and CO Binding Properties of the NiFe Complex in Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum "; Woonsup Shin and Paul A. Lindahl Biochemistry, 1992, 31, 12870 - 12875.

"Redox Titrations of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum "; Woonsup Shin, Philip R. Stafford, and Paul A. Lindahl, Biochemistry 1992, 31, 6003 - 6011.

"The Amino-Acid-Sequence and Redox Properties of the Eight-Iron Ferredoxin II from Clostridium thermoaceticum" FASEB Journal, 1991, 5, A470.

"Reactivities and Biological Functions of Iron-Sulfur Clusters"; Paul A. Lindahl and Julie A. Kovacs. Journal of Cluster Science 1990, 1, 29 - 73.

"Mössbauer Study of CO Dehydrogenase from Clostridium thermoaceticum"; Paul A. Lindahl, Steve W. Ragsdale, and Eckard Münck, J. Biol. Chem. 1990, 265, 3880 - 3888.

"CO Dehydrogenase from Clostridium thermoaceticum "; EPR and Electrochemical Studies in CO2 and Argon Atmospheres"; Paul A. Lindahl, Eckard Münck, and Steve W. Ragsdale J. Biol. Chem. 1990, 265, 3873 - 3879.

1982-1987

"Mössbauer Studies of the Solid-Thionin Oxidized MoFe Protein of Nitrogenase"; Paul A. Lindahl, Vassilios Papaefthymiou, William H. Orme-Johnson, and Eckard Münck. J. Biol. Chem., 1988, 263, 19412 - 19418.

"Mössbauer and EPR Spectroscopy of CO Dehydrogenase and the Co/Fe-S Protein from Clostridium thermoaceticum "; Paul A. Lindahl, Steve W. Ragsdale, Harland G. Wood, and Eckard Münck. Recl. Trav. Chim. Pays-Bas 1987, 106, 241.

"Mössbauer, EPR, and Optical Studies of the Corrinoid/Iron-Sulfur Protein Involved in the Synthesis of Acetyl-CoA by Clostridium thermoaceticum "; Steve W. Ragsdale, Paul A. Lindahl, and Eckard Münck. J. Biol. Chem. 1987, 262(31), 14289 - 14297.

"EXAFS Studies of the Nitrogenase Iron Protein from Azotobacter vinelandii "; Paul A. Lindahl, Boon K. Teo, and William H. Orme-Johnson. Inorg. Chem. 1987, 26, 3912 - 3916.

"EPR and Mössbauer Studies of Nucleotide-Bound Nitrogenase Iron Protein from Azotobacter vinelandii "; Paul A. Lindahl, Nancy J. Gorelick, Eckard Münck, and William H. Orme-Johnson. J. Biol. Chem. 1987, 262(31), 14945 - 14953.

"SQUID Measurement of Metalloprotein Magnetization: New Methods Applied to the Nitrogenase Proteins"; Edmund P. Day, Thomas A. Kent, Paul A. Lindahl, Eckard Münck, William H. Orme-Johnson, Heinrich Roder and Apurba Roy. Biophysical Journal 1987, 52, 837 - 853.

"Studies of the Metal Cluster in the Iron Protein of Nitrogenase"; Paul A. Lindahl Ph.D. thesis, Massachusetts Institute of Technology, Cambridge MA, 1985.

"Mössbauer, EPR, and Magnetization Studies of the Azotobacter vinelandii Fe Protein"; Paul A. Lindahl, Edmund P. Day, Thomas A. Kent, William H. Orme-Johnson, and Eckard Münck. J. Biol. Chem. 1985, 260(20), 11160 - 11173.

"Nickel and Iron EXAFS of F420-Reducing Hydrogenase from Methanobacterium thermoautotrophicum "; Paul A. Lindahl, Nakao Kojima, Robert P. Hausinger, Judith A. Fox, Boon-Keng Teo, Christopher T. Walsh, and William H. Orme-Johnson. J. Am. Chem. Soc. 1984, 106, 3062.

"Iron EXAFS of the Iron-Molybdenum Cofactor of Nitrogenase"; Mark R. Antonio, Boon-Keng Teo, William H. Orme-Johnson, Mark J. Nelson, Susan E. Groh, Paul A. Lindahl, Susan M. Kauzlarich, and Bruce A. Averill. J. Am. Chem. Soc. 1982, 104, 4703.

"Bioinorganic Chemistry of Nitrogenase"; Mark J. Nelson, Paul A. Lindahl, and William H. Orme-Johnson, in Advances in Inorganic Biochemistry, 1982 Vol. 4; G. L. Eichorn, L. G. Marzilli, Eds., Elsevier Biomedical.