romo

109. Acylammonium Salts as Dienophiles in Diels-Alder/Lactonization Organocascades Abbasov, M. E.; Hudson, B. M.; Tantillo, D. J.; Romo D. J. Am. Chem. Soc. 2014, 136, 4492–4495. [Highlighted in JACS Spotlights]

108. Chemo- and Site-Selective Derivatizations of Natural Products Enabling Biological Studies Robles, O.; Romo D. Nat. Prod. Rep. 2014, 31, 318-334.

107. Second-Generation Derivatives of the Eukaryotic Translation Initiation Inhibitor Pateamine A Targeting eIF4A as Potential Anticancer Agents Low, W.-K.; Li, J.; Zhu, M.; Kommaraju, S. S.; Shah-Mittal, J.; Hull, K.; Liu, J. O.; Romo D. Bioorg. Med. Chem. Lett. 2014, 22, 116-125.

 

106. Rapid Assembly of Complex Cyclopentanes Employing Chiral, α,β-Unsaturated Acylammonium Intermediates Liu, G.; Shirley, M. E.; Van, K. N.; McFarlin, R. L.; Romo, D. Nature Chem., 2013, 5, 1049-1057. [Highlighted in C&EN, BioNewsTexas, and Synform]

105. Direct Catalytic Asymmetric Synthesis of N-Heterocycles from Commodity Acid Chlorides Employing α,β-Unsaturated Acylammoniums Vellalath, S.; Van, K. N.; Romo, D. Angew. Chem. Int. Ed., 2013, 52, 13688–13693. [Highlighted in Synfacts (heterocycles) and Synfacts (organocatalysis)]

104. Interrogating Translational Efficiency and Lineage-Specific Transcriptomes Using Ribosome Affinity Purification Zhou, P.; Zhang, Y.; Ma, Q.; Gu, F. Day, D. S.; He, A.; Zhou, B., Li, J., Stevens, S.; Romo, D.; Pu, W. T. Proc. Nat. Acad. Sci., 2013, 110, 15395-15400.

103. Concise Synthesis of the Isothiourea Organocatalysts Homobenzotetramisole and Derivatives Ranieri, B.; Robles, O.; Romo, D. J. Org. Chem., 2013, 78, 6291-6296.

102. Simultaneous Structure–Activity Studies and Arming of Natural Products by C–H Amination Reveal Cellular Targets of Eupalmerin Acetate Li, J.; Cisar, J.S.; Zhou, C.-Y.; Vera, B.; Williams, H.; Rodrı´guez, A.B.; Cravatt, B.F.; Romo, D. Nature Chem., 2013, 5, 510-517.

 

101. Dyotropic Rearrangements of Fused Tricyclic β-Lactones: Application to the Synthesis of (−)-Curcumanolide A and (−)-Curcumalactone Leverett C.A.; Purohit V.C.; Johnson A.G.; Davis R.L.; Tantillo D.J.; Romo D. J. Am. Chem. Soc., 2012, 134, 13348-13356.

100. Bioinspired Total Synthesis of Agelastatin A Reyes, J.C.P.; Romo, D. Angew. Chem. Int. Ed., 2012, 51, 6870-6873.

99. De Novo Synthesis of Benzosceptrin C and Nagelamide H from 7-15N-Oroidin: Implications for Pyrrole–Aminoimidazole Alkaloid Biosynthesis Stout E.P.; Morinaka, B.I.; Wang, Y.-G.; Romo, D.; Molinski, T.F. J. Nat. Prod., 2012, 75, 527-530.

98. Pyrrole-Aminoimidazole Alkaloid Metabiosynthesis with Marine Sponges Agelas Conifera and Stylissa Caribica Stout, E.P.; Wang, Y.-G.; Romo, D.; Molinski, T.F. Angew. Chem. Int. Ed., 2012, 51, 4877-4881.

97. Cyclopropanations of Olefin-Containing Natural Products for Simultaneous Arming and Structure Activity Studies Robles, O.; Sergio O. Serna-Saldívar, S.O.; Gutiérrez-Uribe, J.A.; Romo, D. Org. Lett., 2012, 14, 1394-1397.

96. A Diastereoselective, Nucleophile-Promoted Aldol-Lactonization of Ketoacids Leading to Bicyclic-β-Lactones Liu, G.; Shirley, M.E.; Romo, D. J. Org. Chem., 2012, 77, 2496-2500.

 

95. Mechanistic Investigations of the ZnCl2-Mediated Tandem Mukaiyama Aldol-Lactonization (TMAL): Evidence for Asynchronous, Concerted Transition States and Discovery of 2-Oxopyridyl Ketene Acetal Variants Zhao, C.; Mitchell, T. A.; Vallakati, R.; Pérez, L. M. Romo, D. J. Am. Chem. Soc., 2011, 134, 3084-3094.

94. Total Synthesis of the Spirocyclic Imine Marine Toxin (-)-Gymnodimine and an Unnatural C4-Epimer Kong, K.; Moussa, Z.; Lee, C.; Romo, D. J. Am. Chem. Soc., 2011, 133, 19844-19856. [Highlighted by Chemistry World in Totally Synthetic (-)-Gymnodimine]

93. Diazo Reagents with Small Steric Footprints for Simultaneous Arming/SAR Studies of Alcohol-Containing Natural Products via OH Insertion Chamni, S.; He, Q.L.; Dang, Y.; Bhat, S.; Liu, J.O.; Romo, D. ACS Chem. Biol., 2011, 6, 1175-1181. [Featured on Issue 11, 2011 Front Cover]

92. Switching Between Concerted and Stepwise Mechanisms for Dyotropic Rearrangements of β-Lactones Leading to Spirocyclic, Bridged γ-Butyrolactones Davis, R.; Leverett, C.; Romo, D.; Tantillo, D. J. Org. Chem., 2011, 76, 7167-7174.

91. Total Synthesis of (+)-Omphadiol Liu, G.; Romo, D. Angew. Chem. Int. Ed., 2011,123, 7679-7682. [Featured on Issue 33, 2011 Front Cover and Highlighted in Synfacts 2011, 10, 1043]

90. Biosynthesis, Asymmetric Synthesis, and Pharmacology Including Cellular Targets of the Pyrrole-2-Aminoimidazole Marine Alkaloid Al-Mourabit, A.; Zancanella, M.; Tilvi, S.; Romo, D. Nat. Prod. Rep., 2011, 28, 1229-1260. [Featured on Issue 7, 2011 Front Cover]

89. Organocatalytic Enantioselective Synthesis of Bicyclic β-Lactones Via Nucleophile-Catalyzed Aldol-Lactonization (NCAL) Nguyen, H.; Oh, S.; Henry-Riyad, H.; Sepulveda, D.; Romo, D. Org. Syn., 2011, 88, 121-137.

88. Marinobufagenin Levels in Preeclamptic Patients: A Preliminary Report Horvat, D.; Harrison, R.; Uddin, M.N.; Jones, R.; Abi Ghanem, D.; Berghman, L.C.; Lai, X.Z.; Li, J.; Romo, D.; Puschett, J.B. Amer. J. Perinatology, 2011, 28, 509-514.

87. A Chemifluorescent Immunoassay for the Determination of Marinobufagenin in Body Fluids Abi-Ghanem, D.; Lai, X.Z.; Berghman, L.R.; Horvat, D.; Li, J.; Romo, D.; Uddin, M.N.; Kamano, Y .; Nogawa, T.; Xu, J.P.; Pettit, G.R.; Puschett, J.B. J. Immunoassay Immunochem., 2011, 32, 31-46.

86. Bioinspired Total Synthesis and Human Proteasome Inhibitory Activity of (-)-Salinosporamide A, (-)-Homosalinosporamide A, and Derivatives Obtained via Organonucleophile Promoted Bis-Cyclizations Nguyen, H.; Ma, G.; Fremgen,T.; Gladysheva, T.; Romo, D. J. Org. Chem., 2011, 76, 2-12. [Featured on Issue 1, 2011 Front Cover]

 

85. Enantioselective, Organocatalyzed Intramolecular Aldol-Lactonizations with Ketoacids Leading to Bicyclic and Tricyclic β-Lactones and Topology Morphing Transformations Leverett, C.A.; Purohit, V.C.; Romo, D. Angew. Chem. Int. Ed., 2010, 49, 9479-9483. [Highlighted in Synfacts 2011, 1, 99]

84. Cyclosporin A Treatment of Leishmania Donovani Reveals Stage-Specific Functions of Cyclophilins in Parasite Proliferation and Viability Yau, W.L.; Blisnick, T.; Taly, J.F.; Helmer-Citterich, M.; Schiene-Fischer, C.; Leclercq, O.; Li, J.; Schmidt-Arras, D.; Morales, M.A.; Notredame, C.; Romo, D.; Bastin, P.; Spath, G.F. Plos Negl. Trop. Dis., 2010, 4, e729.

83. Double Diastereoselective, Nucleophile-Catalyzed Aldol Lactonizations (NCAL) Leading to β-Lactone Fused Carbocycles and Extensions to β-Lactone Fused Tetrahydrofurans Morris, K. A.; Arendt, K.; Oh, S.; Romo, D. Org. Lett., 2010, 12, 3764-3767.

82. A1,3-Strain Enabled Retention of Chirality During Bis-Cyclization of β-Ketoamides: Total Synthesis of (–)-Salinosporamide A and (–)-Homosalinosporamide A Nguyen, H.; Ma, G.;Romo, D. Chem. Comm., 2010, 46, 4803-4805.

81. Mild Arming and Derivatization of Natural Products via an In(OTf)3-Catalyzed Arene Iodination Zhou, C-Y; Li, J.; Peddibhotla, S.; Romo, D. Org. Lett., 2010, 12, 2104-2107.

80. Synthesis of 7-15N-Oroidin and Evaluation of Utility for Biosynthetic Studies of Pyrrole-Imidazole Alkaloids by Microsale 1H-15N HSQC and FTMS Wang, Y.; Morinaka, B.I.; Reyes, J.C.P.; Wolff, J. H.; Romo, D.; Molinski, T. F. J. Nat. Prod., 2010, 73, 428-434.

 

79. Enantioselective Total Synthesis of the Marine Toxin (-)-Gymnodimine Employing a Barbier-Type Macrocyclization Kong, K.; Lee, C.S.; Romo, D. Agnew. Chem. Int. Ed., 2009, 121, 7538-7541. [Highlighted in Synfacts 2010, 1, 15]

78. Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A Through Eukaryotic Initiation Factor 4AIII Dang, Y.; Low, W-K.; Xu, J.; Gehring, N. H.; Dietz, H.C.; Romo, D.; Liu, J.O. J. Biol. Chem., 2009, 35, 23613-23621.

77. Asymmetric Synthesis, Structure, and Reactivity of Unexpectedly Stable Spiroepoxy-β-Lactones Including Facile Conversion to Tetronic Acids: Application to (+)-Maculalactone A Duffy, R. J.; Morris, K.A.; Vallakati, R.; Zhang, W.; Romo, D. J. Org. Chem., 2009, 74, 4772-4781.

76. Synthesis of Unusually Strained Spiro Ring Systems and Their Exploits in Synthesis Duffy, R. J.; Morris, K. A.; Romo, D. Tetrahedron 2009, 65, 5879-5892.

75. Potent In Vitro and In Vivo Anticancer Activities of Des-methyl, Des-amino Pateamine A, a Synthetic Analogue of Marine Natural Product Pateamine A Kuznetsv, G.; Xu,Q.;Rudolph-Owen,L.; TenDyke, K.; Liu, J.; Towle, M.; Zhao, N.; Marsh, J.; Agoulnik, S.; Twine, N.; Parent, L.; Chen, Z.; Shie, J.; Jian, Y.; Zhang, H.; Du, H.; Boivin, R.; Wang, Y.; Romo, D.; Littlefield, B. Mol Cancer Ther., 2009, 8, 1250-1260.

74. Enantioselective Synthesis of Schulzeines B and C via a Beta-Lactone-Derived Surrogate for Bis-homoserine Aldehyde Romo, D.; Liu, G. Org. Lett., 2009, 11, 1143-1146.

 

73. Diastereoselective, Three-Component, Cascade Synthesis of Tetrahydrofurans and Tetrahydropyrans Employing the Tandem Mukaiyama Aldol-Lactonization (TMAL) Process Mitchell, T. A.; Zhao, C.; Romo, D. J. Org. Chem., 2008, 73, 9544-9551.

72. Recent Advances in Lewis Base-Catalyzed, Stereoselective Aldol β- and γ- Lactonizations Purohit, V. C.; Matla, A. S.; Romo, D. Heterocycles 2008, 76, 949-979.

71. Concise Synthesis of Spirocyclic, Bridged γ-Butrolactones via Stereospecific, Dyotropic Rearrangements of β-Lactones Involving 1,2-Acyl and δ-Lactone Migrations Purohit, V. C.; Matla, A. S.; Romo, D. J. Am. Chem. Soc., 2008, 130, 10478-10479.

70. Synthesis of Novel β-Lactone Inhibitors of Fatty Acid Synthase Richardson, R. D.; Ma, G.; Oyola, Y.; Zancanella, M. A.; Knowles, L. M.; Cieplak, P.; Romo, D.; Smith, J. W. J. Med. Chem., 2008, 51, 5285-5296.

69. Facile Sythesis of the Trans-Fused Azabicyclo[3.3.0]octane Core of Palau’amine and the Tricyclic Core of Axinellamine from a Common Intermediate Zancanella, M. A.; Romo, D. Org. Lett., 2008, 10, 3685-3688.

68. Highly Diastereoselective, Tandem, Three-Component Synthesis of Tetrahydrofurans from Ketoaldehydes via Silylated β-Lactone Intermediates: Application to a Colpsinol B Fragment Mitchell, T. A.; Zhao, C.; Romo, D. Angew. Chem. Int. Ed., 2008, 47, 5026-5029.

67. β-Lactam Congeners of Orlistat as Inhibitors of Fatty Acid Synthase Zhang, W.; Richardson, R. D.; Chamni, S.: Smith, J. W.; Romo, D. Bioorg. Med. Chem. Lett., 2008, 28, 2491-2494. [Highlighted in C&EN, June 23, 2008]

66. Enantioselective Synthesis of (+)-Monobromophakellin and (+)-Phakellin: A Concise Phakellin Annulation Strategy Applicable to Palau'amine Wang, S.; Romo, D. Angew. Chem. Int. Ed., 2008, 47, 1284-1286. [Highlighted in Synfacts 2008, 7, 678]

 

65. Synthesis of a Cyclic Guanidine Hemiaminal Pertinent to the Axinellamines Tang, L.; Romo, D. Heterocycles 2007, 74, 999-1008.

64. Diastereoselective Synthesis of Tetrahydrofurans via Mead Reductive Cyclization of Keto-β-Lactones Derived from the Tandem Mukaiyama Aldol Lactonization (TMAL) Process Mitchell, T. A.; Romo, D. J. Org. Chem., 2007, 72, 9053-9059. [Highlighted in Organic Chemistry Portal: Organic Chemistry Highlights, April 14, 2008]

63. Transformation of Fused Bicyclic and Tricyclic β-Lactones to Fused γ-Lactones and 3(2H)-Furanones via Ring Expansions and O−H Insertions Zhang, W.; Romo, D. J. Org. Chem., 2007, 72, 8939-8942.

62. Simultaneous Arming and Structure/Activity Studies of Natural Products Employing O-H Insertions: An Expedient and Versatile Strategy for Natural Products-Based Chemical Genetics Peddibhotla, S.; Dang, Y.; Liu, J. O.; Romo, D. J. Am. Chem. Soc., 2007, 129, 12222-12231. [Highlighted in C&EN, October 1, 2007]

61. Substrate-Dependent Targeting of Eukaryotic Translation Initiation Factor 4A by Pateamine A: Negation of Domain-Linker Regulation of Activity Low, W.-K.; Dang, Y.; Bhat, S.; Romo, D.; Liu, J. O. Chem. & Biol., 2007, 14, 1-13.

60. Alkyl C-O Ring Cleavage of Bicyclic β-Lactones with Normant Reagents: Synthesis of Merck IND Intermediate Zhang, W.; Matla, A. S.; Romo, D. Org. Lett., 2007, 9, 2111-2114. [Highlighted in Organic Chemistry Portal: Organic Chemistry Highlights, December 10, 2007]

59. Concise Total Synthesis of (±)-Salinosporamide A, (±)-Cinnabaramide A, and Derivatives via a Bis-cyclization Process:  Implications for a Biosynthetic Pathway? Ma, G.; Nguyen, H.; Romo, D. Org. Lett., 2007, 9, 2143-2146. [Highlighted in Synfacts 2007, 10, 1014]

58. Total Synthesis of (−)-Belactosin C and Derivatives via Double Diastereoselective Tandem Mukaiyama Aldol Lactonizations Cho, S. W.; Romo, D. Org. Lett., 2007, 9, 1537-1540. [Highlighted in Synfacts 2007, 8, 789]

57. Isolation and Identification of Eukaryotic Initiation Factor 4A as a Molecular Target for the Marine Natural Product Pateamine A Low, W.-K.; Dang, Y.; Schneider-Poetsch, T.; Shi, Z.; Choi, N. S.; Rzasa, R. M.; Shea, H. A.; Li, S.; Park, K.; Ma, G.; Romo, D.; Liu, J. O. Methods in Enzymology 2007, 431, 303-324.

 

56. Eukaryotic Initiation Factor 2α-independent Pathway of Stress Granule Induction by the Natural Product Pateamine A Dang Y.; Kedersha, N.; Low, W.-K.; Romo, D.; Gorospe, M.; Kaufman, R.; Anderson, P.; Liu, J. O. J. Biol. Chem., 2006, 281, 32870-32878.

55. Synthesis, Characterization, and Utility of Thermoresponsive Natural/Unnatural Product Macroligands for Affinity Chromatography Zhou, M.; Sivaramakrishnan, A.; Ponnamperuma, K.; Low, W.-K.; Li, C.; Zhang, Y.; Liu, J. O.; Bergbreiter, D.; Romo, D. Org. Lett., 2006, 8, 5247-5250.

54. Total Synthesis and Comparative Analysis of Orlistat, Valilactone, and a Transposed Orlistat Derivative: Inhibitors of Fatty Acid Synthase Ma, G.; Zancanella, M.; Oyola, Y.; Richardson, R. D.; Smith, J. W.; Romo, D. Org. Lett., 2006, 8, 4497-4500.

53. Bicyclic- and Tricyclic-β-Lactones via an Organonucleophile Bis-cyclization of Keto-Acids: Enantioselective Synthesis of (+)-Dihydroplakevulin Henry-Riyad, H.; Lee, C. S.; Purohit, V.; Romo, D. Org. Lett., 2006, 8, 4363-4366.

52. Mild Deprotection of Primary N-(p-Toluenesulfonyl) Amides with SmI2 Following Trifluoroacetylation Moussa, Z.; Romo, D. Synlett 2006, 19, 3294-3298.

51. Diastereoselective, Vinylogous Mukaiyama Aldol Addition of Silyloxy Furans to Cyclic Ketones: Annulation of Butenolides and γ-Lactones Kong, K.; Romo, D. Org. Lett., 2006, 8, 2909-2912.

50. Planned and Unplanned Halogenations in Route to Selected Oroidin Alkaloids Wang, S.; Poullennec, K. G.; Dilley, A. S.; Romo, D. Tetrahedron 2006, 62, 7155-7161.

49. Practical, Catalytic, Asymmetric Synthesis of β-Lactones via a Sequential Ketene Dimerization/Hydrogenation Process: Inhibitors of the Thioesterase Domain of Fatty Acid Synthase Purohit, V. C.; Richardson, R. D., Smith, J. W.; Romo, D. J. Org. Chem., 2006, 71, 4549-4558.

48. A Unified Synthetic Stratgy Toward Oroidin Derived Alkaloids Premised on a Biosynthetic Proposal Dransfield, P. J.; Dilley, A. S.; Wang, S.; Romo, D. Tetrahedron 2006, 62, 5223-5247. [Bioinspired Approaches to Chemical Synthesis, invited paper]

 

47. Inhibition of Eukaryotic Translation Initiation by the Marine Natural Product Pateamine A Low, W.-K.; Dang, Y.; Schneider-Poetsch, T.; Shi, Z; Choi, N. S.; Merrick, W. C.; Romo, D.; Liu, J. O. Mol. Cell 2005, 20, 709-722. [Highlighted in C&EN, December 19, 2005 and Featured in Chem. Biol. (Viewpoint by J. Clardy), 2006, 1, 17]

46. Synthesis, Structure, and Reactivity of Unexpectedly Stable Spiroepoxy-β-Lactones Obtained by Epoxidation of 4-Alkylidene-2-Oxetanones Duffy, R. J.; Morris, K. A.; Romo, D. J. Am. Chem. Soc., 2005, 127, 16754-16755.

45. Radical Reactions and a-Silylations of Optically Active 4-Trichloromethyl-β-Lactone Mitchell, A. T.; Romo, D. Heterocycles 2005, 66, 627-637. [Invited Paper]

44. Studies Toward a Marine Toxin Immunogen: Enantioselective Synthesis of the Spirocyclic Imine of (-)-Gymnodimine Kong, K.; Moussa, Z.; Romo, D. Org. Lett., 2005, 7, 5127-5130.

43. Asymmetric Synthesis of Bicyclic β-Lactones via the Intramolecular, Nucleophile-Catalyzed Aldol-lactonization (NCAL): Improved Efficiency and Expanded Scope Oh, S.; Cortez, G.; Romo D. J. Org. Chem., 2005, 70, 2835-2838. [Highlighted in Organic Chemistry Portal: Organic Chemistry Highlights, December 19, 2005]

42. Highly Regioselective Diels-Alder Reactions toward Oroidin Alkaloids: Use of a Tosylvinyl Moiety as a Nitrogen Masking Group with Adjustable Electronics Dransfield, P. J.; Wang, S.; Dilley, A.; Romo, D. Org. Lett., 2005, 7, 1679-1682.

 

41. β-Lactones: Intermediates for Natural Product Total Synthesis and New Transformations Wang, Y.; Tennyson, R.; Romo, D. Heterocycles 2004, 64, 605-658.

40. Evidence for Separate Binding and Scaffolding Domain in the Immunosuppressive and Antitumor Marine Natural Product, Pateamine A: Design, Synthesis, and Activity Studies Leading to a Potent, Simplified Derivative Romo, D.; Choi, N. S.; Buchler, I. P.; Shi, Z.; Liu, J. O. J. Am. Chem. Soc., 2004, 126, 10582-10588.

 

39. Enantioselective Total Synthesis of (+)-Dibromophakellstatin Poullenec, K.; Romo, D. J. Am. Chem. Soc., 2003, 125, 6344-6345.

 

38. Concise Total Synthesis of (+)-Brefeldin A:  A Combined β-Lactone/Cross-Metathesis-Based Strategy Wang, Y.; Romo, D. Org. Lett., 2002, 4, 3231-3234.

37. Highly Diastereoselective Desymmetrizations of Cyclo(Pro,Pro):  An Enantioselective Strategy Toward Phakellstatin and Phakellin Poullennec, K. G.; Kelly, A. T.; Romo, D. Org. Lett., 2002, 4, 2645-2648.

36. Nucleophilic Openings of Bicyclic β-Lactones via Acyl C-O and Alkyl C-O Cleavage: Catalytic, Asymmetric Synthesis of a Versatile, Carbocyclic Nucleoside Precursor and Protected Transpentenic Acid Yokota, Y.; Cortez, G. S.; Romo, D. Tetrahedron: Symposium in Print "Application of Strained Heterocycles as Reactive Intermediates in Organic Synthesis" Tetrahedron 2002 58, 7075-7080.

35. Mechanism and Origin of Stereoselectivity in Lewis Acid-Catalyzed [2+2] Cycloadditions of Ketenes with Aldehydes Singleton, D. A.; Wang, Y.; Yang, H. W.; Romo, D. Angew. Chem. Int. Ed., 2002, 41, 1572-1575.

34. A β-Lactone Route to Chiral γ-Substituted α-Amino Acids: Application to the Concise Synthesis of (S)- α-Azidobutyro Lactone and a Natural Amino Acid Tennyson, R.; Cortez, G. C.; Galicia, H. J.; Kreiman, C. R.; Thompson, C. M.; Romo, D. Org. Lett., 2002, 4, 533-536.

 

33. Bicyclic β-Lactones via Intramolecluar NCAL Reactions with Cinchona Alkaloids: Effect of the C9-Substitutent on Enantioselectivity and Catalyst Conformation Cortez, G. S.; Oh S.-H.; Romo, D. Synthesis (Special Topics) 2001, 1731-1736.

32. Intramolecular Nucleophile Catalyzed Aldol-Lactonization (NCAL) Reactions: Catalytic, Asymmetric Synthesis of Bicyclic β-Lactones Cortez, G. S.; Tennyson, R.; Romo, D. J. Am. Chem. Soc., 2001, 123, 7945-7946. [Feature in Angew. Chem. Int. Ed. Highlights Article, Angew. Chem. Int. Ed., 2002, 41, 744-746]

31. Enantioselective Strategy to the Spirocyclic Core of Palau'amine and Related Bisguanidine Marine Alkaloids Dilley, A. S.; Romo, D. Org. Lett., 2001, 3, 1535-1538.

30. The Incredible Power of Organic Synthesis Romo, D. New Voices in Chemistry, Chemical and Engineering News-125th Anniversary Issue, March 26, 2001.

29. Studies Toward Gymnodimine: Development of a Single-Pot Hua Reaction for the Synthesis of Highly Hindered Cyclic Imines Ahn, Y.; Cardenas, G.; Yang, J.; Romo, D. Org. Lett., 2001, 3, 751-754.

 

28. Use of In Situ Generated Ketene in the Wynberg β-Lactone Synthesis: New Transformations of the Dichlorinated β-Lactone Products Tennyson, R.; Romo, D. J. Org. Chem., 2000, 65, 7248-7252.

27. "Total Synthesis of Marine Natural Products Driven by Novel Structure, Potent Biological Activity, and/or Synthetic Methodology" In The Role of Natural Products in Drug Discovery, Romo, D.; Rzasa, R. M.; Schmitz, W. D.; Yang, J.; Cohn, S. T.; Buchler, I. P.; Shea, H. A.; Park, K.; Langehan, J. M.; Messerchmidt, N. B.; Cox, M. M., Mulzer, J.; Bohlmann, R., Eds.; Ernst Schering Research Foundation Workshop 32, Springer-Verlag Publishers, Berlin, Germany, 2000.

26. Studies Toward (-)-Gymnodimine: Concise Routes to the Tetrahydrofuran and Spirocyclic Moieties Yang, J.; Cohn, S.; Romo, D. Org. Lett., 2000, 2, 763-767.

 

25. A Stereocomplementary Approach to β-Lactones: Highly Diastereoselective Synthesis of cis-β-Lactones, a β-Chloroacid, and a Tetrahydrofuran Wang, Y.; Zhao, C.; Romo, D. Org. Lett., 1999, 1, 1197-1199.

24. A Single Pot, Mild Conversion of β-Lactones to β-Lactams Yang, H. W.; Romo, D. J. Org. Chem., 1999, 64, 7657-7660.

23. Methods for the Synthesis of Optically Active β-Lactones (2-Oxetanones) Yang, H. W.; Romo, D. Tetrahedron 1999, 55, 6403-6434.

 

22. Total Synthesis and Immunosuppressive Activity of (-)-Pateamine A and Related Compounds: Implementation of a β-Lactam-Based Macrocyclization Romo, D.; Rzasa, R. M.; Shea, H. A.; Park, K.; Langehan, J. M.; Sun, L.; Akhiezer, A.; Liu, J. O. J. Am. Chem. Soc., 1998, 120, 12237-12254.

21. Synthesis and Inhibitory Action on HMG-CoA Synthase of Racemic and Optically Active Oxetan-2-ones (β-Lactones) Romo, D.; Harrison, P. H. M.; Jenkins, S. I.; Riddoch, R. W.; Park, K. P.; Yang, H. W.; Zhao, C.; Wright, G. D. Bioorg. Med. Chem., 1998, 6, 1255-1272.

20. Simultaneous Deprotection and Purification of BOC-amines Based on Ionic Resin Capture Liu, Y.-S.; Zhao, C.; Bergbreiter, D. E.; Romo, D. J. Org. Chem., 1998, 63, 3471-3473.

19. Studies of the Asymmetric [2+2] Cycloaddition of Silylketenes and Aldehydes Employing Ti-TADDOL Catalysts Yang, H. W.; Romo, D. Tetrahedron Lett., 1998, 39, 2877-2880.

18. A β-Lactone-Based Strategy Applied to the Total Synthesis of (8S,21S,22S,23R)- and (8R,21S,22S,23R)-Okinonellin B Schmitz, W. D.; Messerschmidt, B.; Romo, D. J. Org. Chem., 1998, 63, 2058-2059.

17. Practical, One-Step Synthesis of Optically Active β-Lactones via the Tandem Mukaiyama Aldol-Lactonization (TMAL) Reaction Yang, H. W.; Romo, D. J. Org. Chem., 1998, 63, 1344-1347.

16. Total Synthesis of the Novel, Immunosuppressive Agent (−)-Pateamine A from Mycale sp. Employing a β-Lactam-Based Macrocyclization Rzasa, R. M.; Shea, H. A.; Romo, D. J. Am. Chem. Soc., 1998, 120, 591-592.

 

15. A β-Lactone-Based Route to Cyclopentanes via Intramolecular Allylsilane Additions. An Unexpected Friedel-Crafts Alkylation Zhao, C.; Romo, D. Tetrahedron Lett., 1997, 38, 6537-6540.

14. Studies of the Tandem Mukaiyama Aldol-Lactonization (TMAL) Reaction: A Concise and Highly Diastereoselective Route to β-Lactones Applied to the Total Synthesis of the Potent Pancreatic Lipase Inhibitor, (−)-Panclicin D Yang, H. W.; Zhao, C.; Romo, D. Tetrahedron (Symposium in Print) 1997, 53, 16471-16488.

13. A Highly Diastereoselective, Tandem Mukaiyama Aldol-Lactonization Route to β-Lactones:  Application to a Concise Synthesis of the Potent Pancreatic Lipase Inhibitor, (−)-Panclicin D Yang, H. W.; Romo, D. J. Org. Chem., 1997, 62, 4-5.

 

12. A New Route to 2-Substituted Δ2-Thiazolines: Stille Cross-Couplings of 2-Bromo-Δ2-Thiazolines Schmitz, W. D.; Romo, D. Tetrahedron Lett. 1996, 37, 4857-4860.

11. Tandem Transacylation/Debenzylation of β-Lactones Mediated by FeCl3 Leading to γ- and δ-Lactones: Application to the Synthesis of (-)-Grandinolide Zemribo, R.; Champ, M. S.; Romo, D. Synlett 1996, 278-280.

 

10. Highly Diastereoselective [2+2] Cycloadditions via Chelation Control: Asymmetric Synthesis of β-Lactones Zemribo, R. and Romo, D. Tetrahedron Lett., 1995, 36, 4159-4162.

9. Structural and Synthetic Studies of the Pateamines: Synthesis and Absolute Configuration of the Hydroxy Dienoate Fragment Rzasa, R. M.; Romo, D.; Stirling, D.; Blunt, J. W.; Munro, M. H. G. Tetrahedron Lett., 1995, 36, 5307-5310.

 

8. Synthesis, Structure and Mechanism in Immunophilin Research Belshaw, P. J.; Meyer, S. D.; Johnson, D. D.; Romo, D.; Ikeda, Y.; Andrus, M.; Alberg, D. G.; Schultz, L. W.; Clardy, J.; Schreiber, S. L. Synlett 1994, 381-392.

7. Total Synthesis of (-)-Rapamycin Using an Evans-Tischenko Fragment Coupling Romo, D.; Meyer, S. D.; Johnson, D. D.; Schreiber, S. L. J. Am. Chem. Soc., 1993, 115, 7906-7907.

6. Synthetic Investigations of Rapamycin. 2. Synthesis of a C(22)-C(42) Fragment Romo, D.; Johnson, D. D.; Plamondon, L.; Miwa, T.; Schreiber, S. L. J. Org. Chem., 1992, 57, 5060-5063.

 

5. An Asymmetric Route to Enantiomerically Pure 1,2,3-Trisubstituted Cyclopropanes Romo, D.; Meyers, A. I. J. Org. Chem., 1992, 57, 6265-6270.

4. Chiral Non-Racemic Bicyclic Lactams. Vehicles for the Construction of Natural and Unnatural Products Containing Quaternary Carbon Centers Romo, D.; Meyers, A. I. Tetrahedron 1991, 47, 9503-9569.

3. Diastereoselective Cyclopropanations of Chiral Bicyclic Lactams Leading to Enantiomerically Pure Cyclopropanes. Application to the Total Synthesis of cis-(1S,3R)-Deltamethrinic acid and R-(-)-Dictyopterene C Romo, D.; Romine, J. L.; Midura, W.; Meyers, A. I. Tetrahedron 1990, 46, 4951-4994.

2. Chiral Bicyclic Lactams. Asymmetric Synthesis of cis-(1S,3R)-Deltamethrinic Acid Meyers, A. I.; Romo, D. Tetrahedron Lett., 1989, 30, 1745-1748.

 

1. Effects of Analogs of the Fungal Sexual Pheromone Sirenin on Male Gamete Motility in Allomyces Macrogynus Pommerville, J. C.; Strickland, J. B.; Romo, D.; Harding, K. E. Plant Physiology 1988, 88, 139-142.