Sczepanski Research Group

Department of Chemistry

Group Focus

Our research program is focused on:

  • understanding of the molecular mechanisms underlying the regulation of DNA repair within chromatin
  • the development of L-RNA-based affinity reagents and catalysts for practical biomedical applications
  • understanding how oligonucleotides of opposite stereochemistry interact, both in terms of molecular recognition and catalysis.
By combining expertise in nucleic acid chemistry, molecular biology, and directed evolution, we are able to address challenges associated with studying and targeting nucleic acids and related processes from a unique perspective. For more information on our projects, click here