Suggested Reading

            There is no assigned text for the course, rather, the information will be taught from examples of recent advances reported in the current scientific literature and/or drawn from various textbook sources. 

A few reference books include:

Jain, Kewal K.  The Handbook of Nanomedicine.  Humana Press, 2008.  ISBN-13: 978-1-6032-7318-3.

Nanomedicine Design of Particles, Sensors, Motors, Implants, Robots, and Devices.  Ed. Mark J. Schulz, Vesselin N. Shanov, and Yeoheung Yun.  Artech House, 2009.  ISBN-13: 978-1-5969-3279-1.

Nanotechnology:  Volume 5:  Nanomedicine.  Ed. Viola Vogel.  Weinheim:  Wiley-VCH Verlag GmbH & Co. KGaA, 2009.  ISBN-13: 978-3-5273-1736-3.

Nanotechnology in Biology and Medicine:  Methods, devices, and applications.  Ed. Tuan Vo-Dinh.  Boca Raton, FL:  CRC Press, Taylor & Francis Group, 2007.  ISBN-13: 978-0-8493-2949-4.

Tibbals, Harry F.  Perspectives in Nanotechnology:  Medical Nanotechnology and Nanomedicine.  Ed. Gabor L. Hornyak.  Boca Raton, FL:  CRC Press, Taylor & Francis Group, 2011.  ISBN-13: 978-1-4398-0874-0.

Articles Suggested By The Lecturers (click to get pdf)

Bedikian, A. Y.; Del Vecchio, M. "Allovectin-7 therapy in metastatic melanoma", Expert Opin. Biol. Ther., (2008) 8(6), 839-844.

"Alnylam's ALN-VSP Abstract Published by American Society of Clincal Oncology (ASCO)",, 18 May 2011 <>.

Shi, J.; Xiao, Z.; Kamaly, N.; Farokhzad, O. C.; "Self-Assembled Targeted Nanoparticles: Evolution of Technologies and Bench to Bedside Translation", Acc. Chem. Res., (2011) in press.

Jain, K. K.; "Advances in the field of nanooncology", BMC Medicine, (2010), 8(83).

Leroux, J.; "Injectable nanocarriers for biodetoxification", Nature Nanotechnology, (2007), 2, 679-684.

Dreaden, E. C.; Mackey, M. A.; Huang, X.; Kang, B.; El-Sayed, M. A.; "Beating cancer in multiple ways using nanogold"; Chem. Soc. Rev., (2011), 40, 3391–3404.

Lammers, T.; Kiessling, F.; Hennick, W. E.; Storm, G.; "Nanotheranostics and Image-Guided Drug Delivery: Current Concepts and Future Directions", Molecular Pharmaceutics, (2010), 7(6), 1899-1912.

Welch, M. J.; Hawker, C. J.; Wooley, K. L.; "The Advantages of Nanoparticles for PET", J. Nucl. Med., (2009), 50(11), 1743-1746.

Kim, B. Y. S.; Rutka, J. T.; Chan, W. C. W.; "Nanomedicine", N. Engl. J. Med., (2010), 363(25), 2434-2443.

Matsumura, Y.; Hamaguchi, T.; Ura, T.; Muro, K.; Yamada, Y.; Shimada, Y.; Shirao, K.; Okusaka, T., Ueno, H.; Ikeda, M.; Wantanabe, N.; "Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin", British Journal of Cancer, (2004), 91, 1775-1781.

Li, C.; Wallace, S.; "Polymer-Drug Conjugates: Recent Development in Clinical Oncology", Adv. Drug Deliv. Rev., (2008), 60(8), 886-898.

Matsumura, Y.; "Polymeric Micellar Delivery Systems in Oncology", Jpn. J. Clin. Oncol., (2008), 38(12), 793-802.

Nyström, A. M.; Wooley, K. L. “The Importance of Chemistry in Creating Well-defined Nanoscopic Embedded Therapeutics:  Devices capable of the dual functions of imaging and therapy”, Acc. Chem. Res., 2011, in press.

Geng, Y.; Dalhaimer, P.; Cai, S.; Tsai, R.; Tewari, M.; Minko, T.; Discher, D.; "Shape effects of filaments versus spherical particles in flow and drug delivery", Nature Nanotechnology, (2007), 2(4), 249-255.

O'Reilly, R.; Hawker, C. J.; Wooley, K. L.; "Cross-linked block copolymer micelles: functional nanostructures of great potential and versatility", Chem. Soc. Rev., (2006), 35, 1068-1083.

Timko, B. P.; Whitehead, K.; Gao, W.; Kohane, D. S.; Farokhzad, O.; Anderson, D.; Langer, R.; "Advances in Drug Delivery", Annu. Rev. Mater. Res., (2011), 41, 1-20.


Farokhzad, O. C.; Cheng, J.; Teply, B. A.; Sherifi, I.; Jon, S.; Kantoff, P. W.; Richie, J. P.; Langer, R.; "Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo", PNAS, (2006), 103(16), 6315-6320.

Product Information for DOXIL® (doxorubicin HCL liposome injection)

Product Information for ABRAXANE® for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound)

Product Information for ONCASPAR® (pegaspargase)


Harisinghani, M. G.; Barentsz, J.; Hahn, P. F.; Deserno, W. M.; Tabatabaei, S.; Hulsbergen van de Kaa, C.; de la Rosette, J,; Weissleder, R.; "Noninvasive Detection of Clinically Occult Lymph-Node Metastases in Prostate Cancer", N Engl J Med, (2003), 348, 2491-2499.

Weissleder, R.; Kelly, K.; Sun, E. Y.; Shtatland, T.; Josephson, L.; "Cell-specific targeting of nanoparticles by multivalent attachment of small molecules", Nature Biotechnology, (2005), 23(11), 1418-1423.

Weissleder, R., "Molecular Imaging in Cancer", Science, (2006), 312, 1168-1171.


Thakor, A. S.; Jokerst, J.; Zavaleta, C.; Massoud, T. F.; Gambhir, S. S., "Gold Nanoparticles: A Revival in Precious Metal Administration to Patients", Nano Lett, (2011), XXXX, 000-000.

Wiedenmann, J.; Oswald, F.; Nienhaus, G. U., "Fluorescent Proteins for Live Cell Imaging: Opportunities, Limitations, and Challanges", Life, (2009), 61(11), 1029-1042.


Ruoslahti, E.; Bhatia, S. N.; Sailor, M. J., "Targeting of drugs and nanoparticles to tumors", J. Cell Biol., (2010), 188(6), 759-768.

10/28/2011 - Articles for Mini-Review

Welch, M. J.; Hawker, C. J.; Wooley, K. L., "The Advantages of Nanoparticles for PET", J. Nucl. Med., (2009), 50, 1743-1746.

Nyström, A. M.; Wooley, K. L., "The Importance of Chemistry in Creating Well-Defined Nanoscopic Embedded Therapeutics: Devices Capable of the Dual
Functions of Imaging and Therapy", Accounts of Chemical Research, (2011), 44(10), 969-978.