Publications


Co-author of the monthly Highlights in Chemistry and Industry since 1986; now contributing the Biomedical section.

H index 78 as of April 2020

Complete List of Published Works available at:


2020

Unconventional Secondary Structure Mimics: Ladder-rungs
C. M. Lin, M. Arancillo, J. Whisenant, , K. Burgess
Angew. Chem. Int. Ed., 2020, accepted
Lin-2020
Active Targeted Ligand-AzaBODIPY Conjugate for Near-Infrared Photodynamic Therapy in Melanoma
S. Y. Ng, A. Kamkaew, N. Fu, C. S. Kue, L. Y. Chung, L. V. Kiew, J. Wittayakun, K. Burgess, H. B. Lee
Int. J. Pharm., 2020, 579, 119189
Ng-2020
Role Of Albumin Binding In Accumulation And Persistence Of Tumor-seeking Cyanine Dyes
S. M. Usama, G. K. Park, S. Nomura; Y. Baek, H. S. Choi, K. Burgess
Mol. Pharm., 2020, 31, 248-259
Usama-2020

2019

TrkC-Targeted Kinase Inhibitors and PROTACs
B. Zhao and K. Burgess
Mol. Pharm., 2019, 16, 4313-4318
Zhao-2019-1
Cyanine-Gemcitabine Conjugates as Target Theranostic Agents for Glioblastoma tumor Cells
Z. Jiang, K. Pflug, S. M. Usama, D. Kuai, X. Yan, R. Sitcheran, K. Burgess
J. Med. Chem., 2019, 62, 9236-9245
Jiang-2019
Conjugations of Dasatinib With MHI-148 Has a Significant Advantageous Effect in Viability Assays for Glioblastoma Cells
S. M. Usama, Z. Jiang, K. Pflug, R. Sitcheran, K. Burgess
ChemMedChem, 2019, 14, 1575-1579
Usama-2019-1
Protein labelling and albumin binding characteristics of the near-IR Cy7 fluorophore, QuatCy
S. Thavornpradit, S. M. Usama, C.-M. Lin, K. Burgess
Org. Biomol. Chem., 2019, 17, 7150-7154
Thavornpradit-2019-1
Productive Manipulation of Cyanine Dye π-Networks
S. M. Usama, T. Thompson, K. Burgess
Angew. Chem. Int. Ed., 2019, 28, 2-5
Usama-2019-2
Correlations between secondary structure- and protein–protein interface-mimicry: the interface mimicry hypothesis
J. Taechalertpaisarn, R.-L. Lyu, M. Arancillo, C.-M. Lin, L. Perez, T. Ioerger, K. Burgess
Org. Biomol. Chem., 2019, 17, 3267-3274
Taechalertpaisarn-2019-1
A Near‐Infrared Fluorescence Chemosensor Based on Isothiocyanate‐Aza‐BODIPY for Cyanide Detection at the Parts per Billion Level: Applications in Buffer Media and Living Cell Imaging
P. Piyanuch, J. Sirirak, A. Kamkaew, O. Weeranantanapa, V. Promarak, K. Burgess, N. Wanichacheva
ChemPlusChem, 2019, 84, 252-259
Piyanuch-2019
Design criteria for minimalist mimics of protein–protein interface segments
J. Taechalertpaisarn, R.-L. Lyu, M. Arancillo, C.-M. Lin, Z. Jiang, L. Perez, T. Ioerger, K. Burgess
Org. Biomol. Chem., 2019, 17, 908-915
Taechalertpaisarn-2019-2
PROTACs suppression of CDK4/6, crucial kinases for cell cycle regulation in cancer
B. Zhao, K. Burgess
Chem. Commun., 2019, 55, 2704-2707
Zhao-2019-2
QuatCy: A Heptamethine Cyanine Modification With Improved Characteristics
S. Thavornpradit, S. M. Usama, J. P. Shrestha, G. K. Park, H. S. Choi, K. Burgess
Theranostics, 2019, 9, 2856-2867
Thavornpradit-2019-2
A Near-IR Fluorescent Dasatinib Derivative That Localizes in Cancer Cells
S. M. Usama, B. Zhao, K. Burgess
Bioconjugate Chem., 2019, 30, 1175-1181
Usama-2019-3

2018

Site-Specific Labeling of Proteins with Near-IR Heptamethine Cyanine Dyes
C.-M. Lin, S. M. Usama, K. Burgess
Molecules, 2018, 23, 2900
Lin-2018
On the Mechanisms of Uptake of Tumor-seeking Cyanine Dyes
S. M. Usama, C.-M. Lin, K. Burgess
Bioconjugate Chem., 2018, 29, 3886-3895
Usama-2018-1
A Zwitterionic Near-infrared Dye Linked TrkC Targeting Agent for Imaging Metastatic Breast Cancer
Z. Yang, S. M. Usama, F. Li, K. Burgess, Z. Li
Med. Chem. Comm., 2018, 9, 1754-1760
Yang-2018
Targeted Maytansinoid Conjugate Improves Therapeutic Index for Metastatic Breast Cacer Cells
Z. Jiang, Z. Yang, F. Li, Z. Li, N. Fishkin, K. Burgess
Bioconjugate Chem., 2018, 29, 2920-2926
Jiang-2018
Optimized Heptamethine Cyanines for Photodynamic Therapy
S. Usama, S. Thavornpradit, K. Burgess
ACS Appl. Bio Mater., 2018, 1, 1195-1205
Usama-2018-2
A Click-addressable Cassette for Photoaffinity Labeling
B. Zhao, K. Burgess
ACS Med. Chem. Lett., 2018, 9, 155-158
Zhao-2018
Small Molecule Inhibitors of the PCSK9·LDLR Interaction
J. Taechalertpaisarn, B. Zhao, X. Liang, K. Burgesss
J. Am. Chem. Soc., 2018, 140, 3242-3248
Taechalertpaisarn-2018

2017

Near-infrared aza-BODIPY fluorescent probe for selective Cu2+ detection and its potential in living cell imaging
Y. Tachapermpon, S. Thavornpradit, A. Charoenpanich, J. Sirirak, K. Burgess, N. Wanichacheva
Dalton Transactions, 2017, 46, 16251-16256
Tachapermpon-2017
An Agent for Optical Imaging of TrkC-Expressing, Metastatic Breast Cancer
A. Kamkaew, F. Li, Z. Li, K. Burgess
Med. Chem. Commun., 2017, 8, 1946-1952
Kamkaew-2017
Interplay of Stereochemistry, Conformational Rigidity, and Ease of Synthesis for 13-Membered Cyclic Peptidomimetics Containing APC Residues
D. Xin, A. Jeffries, K. Burgess
ACS Comb. Sci., 2017, 19, 414-421
Xin-2017

Selected Publications, Pre-2016

Novel Small Molecule Probes for Metastatic Melanoma
K. Burgess, A. Kamkaew, N. Fu, W. Cai
ACS Med. Chem. Lett., 2016, 8, 179-184
Kamkaew-2016
Extended Piperidine-piperidinone Protein Interface Mimics
D. Xin, A. Raghuraman, K. Burgess
J. Org. Chem., 2015, 80, 4450-4458
Xin-2015
Targeted PDT Agent Eradicates TrkC Expressing Tumors Via Photodynamic Therapy (PDT)
C. S. Kue, A. Kamkaew, H. B. Lee, L. Y. Chung, L. V. Kiew, K. Burgess
Mol. Pharmaceutics, 2015, 12, 212-222
Kue-2015
Small Molecule Probes that Perturb A Protein-protein Interface In Antithrombin
D. Xin, A. Holzenburg, K. Burgess
Chem. Sci., 2014, 5, 4914-4921
Xin-2014-1
A Multi-faced Secondary Structure Mimics Based on Piperidine-Piperidinones
D. Xin, L. M. Perez, T. R. Ioerger, K. Burgess
Angew. Chem., Int. Ed., 2014, 53, 3594-3598
Xin-2014-2
Expanding the Scope of Oligo-pyrrolinone-pyrrolidines as Protein-protein Interface Mimics
A. Raghuraman, D. Xin, L. M. Perez, K. Burgess
J. Org. Chem., 2013, 78, 4823-4833
Raghuraman-2013
Exploring Key Orientations at Protein-Protein Interfaces with Small Molecule Probes
E. Ko, A. Raghuraman, L. M. Perez, T. R. Ioerger, K. Burgess
J. Am. Chem. Soc., 2013, 135, 167-173
Ko-2013
Pyrrolinone-pyrrolidine Oligomers as Universal Peptidomimetics
A. Raghuraman, E. Ko, K. Burgess
J. Am. Chem. Soc., 2011, 133, 12350-12351
Raghuraman-2011
A Combinatorial Method for Solution-phase Synthesis of Labeled Bivalent β-Turn Mimics
Y. Angell, D. Chen, F. Brahimi, H. U. Saragovi, K. Burgess
J. Am. Chem. Soc., 2008, 130, 556-65
Angell-2008
SNAr Cyclization to Form Cyclic Peptidomimetics of β-Turns
Y. Feng, Z. Wang, S. Jin, K. Burgess
J. Am. Chem. Soc., 1998, 120, 10768-9
Feng-1998

Patents

K. Burgess, Inhibitors of LDLR-PCSK9 Protein-Protein Interaction and Methods of Their Use, US Patent No. US10,577,357 B2, World Patent Number WO2018/053517 A1, March, 2020

K. Burgess, S. M. Usama, Conjugates of Kinase Inhibitors and Cyanine Dyes, U. S. Patent Application No.: 16/407,264, May 9, 2019, Publication number US-2019-0343958-A1, No-vember 2019

K. Burgess, Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics With A Third Group, and Methods For Production Thereof, US Patent No. US99,562,023 B2, February 2017

K. Burgess, Peptidomimetic Compounds and Related Methods, US Patent Applica-tion 13866277, Apr 2013.

K. Burgess, Through-Bond Energy Transfer Cassettes, Systems and Methods, US Patent No. US 2009/0192298 A1, July 2009.

K. Burgess, Dipeptide Mimics, Libraries Combining Two Dipeptide Mimics With a Third Group, and Methods for Production Thereof, US Patent No. US 2009/0264315 A1, October 2009.

K. Burgess, Fluorescent Through-Bond Energy Transfer Cassettes Based On Xanthine and Pyronin Derivatives, US Patent No. 7,402,677, July 2008.

K. Burgess, Fluorescent Through-Bond Energy Transfer Cassettes Based On Xanthine and Pyronin Derivatives, US Patent No. US 2005/0032120 A1, February 2005.

K. Burgess, R. Gibbs, et al., Through Bond Energy Transfer in Fluorescent Dyes for Labelling Biological Molecules, US Patent No. US 6,340,750 B1, January 2002.

B. Tamblyn and K. Burgess, New Phosphine Oxazoline Ligand for Chiral Catalysis, US Pa-tent No. US 6472533, December 2002 and Patent MCUS 1455 GB, 1999.

H. Uri Saragovi, K. Burgess, β-Turn Peptidomimetic Cyclic Compounds, Patent WO 01/52843 A1, 2001.


Books

Organic Chemistry By Inquisition, K. Burgess, By Inquisition Press, 2010, 1-600.

Solid-Phase Organic Synthesis, K. Burgess, Ed., Wiley & Sons, New York, 2000, 1-277.


Book Reviews

Book review of "Chiral Ferrocenes in Asymmetric Catalysis: Synthesis and Applications", L.-X. Dai, X.-L. Hou, Eds., Wiley: Weinheim, 2010, J. Am. Chem. Soc., 2010, 132, 10206.

Pseudo-Peptides in Drug Discovery (Book Review), K. Burgess, J. Am. Chem. Soc., 2005, 127, 2365.

Book review of "Combinatorial Chemistry: Synthesis, Analysis, Screening", Günther Jung, Ed., Wiley-VCH, New York, 1999, J. Am. Chem. Soc., 2001.

Book Review of "Combinatorial Chemistry: Synthesis and Application", S. R. Wilson, An. W. Czarnik, Eds., Wiley: New York, 1997, 269 pp., Chem. Education Today, 1998, 75, 289.


The Burgess Lab website created by Rui-Liang Lyu