Home Daniel A. Singleton Research Publications Group Pictures JOC
Publications 1996 - 2000
"Synchronous or Asynchronous? An "Experimental" Transition State from a Direct Comparison of Experimental and Theoretical Kinetic Isotope Effects for a Diels-Alder Reaction," B. R. Beno, K. N. Houk, and D. A. Singleton, J. Am. Chem. Soc. 1996, 118, 9984-5.
"Allylboration of Alkenes with Allyldihaloboranes," D. A. Singleton, S. C. Waller, Z. Zhang, D. E. Frantz, and S. -W Leung, J. Am. Chem. Soc. 1996, 118, 9986-7.
"In Situ Formation of Alkenyl- and Alkynylboranes for Diels-Alder Reactions by Boron-Silicon Exchange with Alkenyl- and Alkynylsilanes," D. A. Singleton and S. -W. Leung, J. Organomet. Chem. 1997, 544, 157-161
"Reactions of Alkynyldihaloboranes with 1,3-Dienes. 1,4-Alkynylborations and Stepwise Diels-Alder Reactions," S. -W. Leung and D. A. Singleton, J. Org. Chem. 1997, 62, 1955-60.
"Cycloalkenylboranes as Highly Reactive and Selective Diels-Alder Dienophiles. A Simple Synthesis of Bridgehead Bicyclic Alcohols," Y. -K. Lee and D. A. Singleton, J. Org. Chem. 1997, 62, 2255-8.
"The Experimental Geometry of the Epoxidation Transition State," D. A. Singleton, S. R. Merrigan, J. Liu, and K. N. Houk, J. Am. Chem. Soc. 1997, 119, 3385-6.
"13C Kinetic Isotope Effects for the Addition of Lithium Dibutylcuprate to Cyclohexenone. Reductive Elimination is Rate-Determining," D. E. Frantz, D. A. Singleton, and J. P. Snyder, J. Am. Chem. Soc., 1997, 119, 3383-4.
"Catalysis by Temporary Covalent Activation. A Novel Catalysis of Unactivated Diels-Alder Reactions," D. A. Singleton, S. -W. Leung, J. P. Martinez, and Y. -K. Lee, Tetrahedron Lett. 1997, 38, 3163.
"Experimental and Theoretical Kinetic Isotope Effects for Asymmetric Dihydroxylation. Evidence Supporting a Rate-Limiting "(3 + 2)" Cycloaddition," A. J. DelMonte, J. Haller, K. N. Houk, K. B. Sharpless, D. A. Singleton, T. Straßner, and A. A. Thomas, J. Am. Chem. Soc. 1997, 119, 9907-9908.
"Deuterium Kinetic Isotope Effects and the Mechanism of the Bacterial Luciferase Reaction," W. A. Francisco, H. M. Abu-Soud, A. J. DelMonte, D. A. Singleton, T. O. Baldwin and F. M. Raushel, Biochemistry 1998, 37, 2596.
"Experimental Proof of the Non-Least Motion Cycloadditions of Dichlorocarbene to Alkenes: Kinetic Isotope Effects and Quantum Mechanical Transition States," A. E. Keeting, S. R. Merrigan, D. A. Singleton, and K. N. Houk, J. Am. Chem. Soc. 1999, 121, 3933-38.
"Stereochemical Labeling at Natural Abundance. Stereochemistry, Isotope Effects, and Mechanism of the Diels-Alder Reaction of Hexachlorocyclopentadiene with Ethyl Vinyl Ether," D. A. Singleton,* S. R. Merrigan, and A. A. Thomas, Tetrahedron Lett. 1999, 40, 639-642.
"Separation of the Primary and Secondary Kinetic Isotope Effects at a Reactive Center Using Starting Material Reactivities. Application to the FeCl3-Catalyzed Oxidation of C-H Bonds with tert-Butyl Hydroperoxide," S. R. Merrigan, V. N. Le Gloahec, J. A. Smith, D. H. R. Barton, and D. A. Singleton, Tetrahedron Lett. 1999, 40, 3847-50.
"Isotope Effects for Lewis Acid-Catalyzed Diels-Alder Reactions. The Experimental Transition State," D. A. Singleton, S. R. Merrigan, B. R. Beno, and K. N. Houk, Tetrahedron Lett. 1999, 40, 5817-21.
"13C and 2H Kinetic Isotope Effects and the Mechanism of Bromination of 1-Pentene under Synthetic Conditions," S. R. Merrigan and D. A. Singleton, Org. Lett. 1999, 1, 327-330.
"Carbometalations of Simple Alkenes with Allyldibromoborane," D. E. Frantz and D. A. Singleton, Org. Lett. 1999, 1, 485-6.
"Evidence for a Concerted Mechanism in a Palladium Trimethylenemethane Cycloaddition," D. A. Singleton and B. E. Schulmeier, J. Am. Chem. Soc. 1999, 121, 9313-9317.
"Nonlinear Effects in Kinetic Resolutions," D. W. Johnson, Jr. and D. A. Singleton, J. Am. Chem. Soc. 1999, 121, 9307-9312.
"Simultaneous Determination of Intermolecular and Intramolecular 13C and 2H Kinetic Isotope Effects at Natural Abundance," D. A. Singleton and M. J. Szymanski, J. Am. Chem. Soc. 1999, 121, 9455-9456.
"Reinvestigation of the Isotope Effects for the Claisen and Aromatic Claisen Rearrangements. The Nature of the Claisen Transition States" M. P. Meyer, A. J. DelMonte, and D. A. Singleton, J. Am. Chem. Soc. 1999, 121, 10865-10874.
"Isotope Effects and the Experimental Transition State for a Prototypical Thermal Ene Reaction," D. A. Singleton and C. Hang, Tetrahedron Lett. 1999, 40, 8939-8942.
"Isotope Effects and the Mechanism of Triazolinedione Ene Reactions. Aziridinium Imides are Innocent Bystanders," D. A. Singleton and C. Hang, J. Am. Chem. Soc. 1999, 121, 11885-11893.
"13C and 2H Kinetic Isotope Effects and the Mechanism of Lewis acid-Catalyzed Ene Reactions of Formaldehyde," D. A. Singleton and C. Hang, J. Org. Chem. 2000, 65, 895-899.
"13C Kinetic Isotope Effects and the Mechanism of the Uncatalyzed Decarboxylation of Orotic Acid," D. A. Singleton, S. R. Merrigan, B. J. Kim, P. Beak, L. M. Phillips, and J. K. Lee, J. Am. Chem. Soc. 2000, 122, 3296-3300.
"Isotope Effects and the Mechanism of Chlorotrimethylsilane-Mediated Addition of Cuprates to Enones," D. E. Frantz and D. A. Singleton, J. Am. Chem. Soc. 2000, 122, 3288-3295.
“Isotope Effects and the Mechanism of Allylic Hydroxylation of Alkenes with Selenium Dioxide,” D. A. Singleton and C. Hang, J. Org. Chem. 2000, 65, 7554-7560.
“Resolution of Conflicting Mechanistic Observations in Ester Aminolysis. A Warning on the Qualitative Prediction of Isotope Effects for Reactive Intermediates,” D. A. Singleton and S. R. Merrigan, J. Am. Chem. Soc. 2000, 122, 11035-6.
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