300. D. F. Xiang, Y. Patskovsky, V. V. Nemmara, S. C. Almo, and F. M. Raushel, “Function Discovery and Structural Characterization of a Methylphosphonate Esterase” Biochemistry 54, 2919-2930 (2015).
299. S. Ghodge and F. M. Raushel, “Discovery of a Previously Unrecognized Ribonuclease from Escherichia coli that Hydrolyzes 5’-Phosphorylated Fragments of RNA" Biochemistry 54, 2911-2918 (2015).
298. S. P. Harvey, M.A. Guelta, F. J. Berg, A. N. Bigley, and F. M. Raushel, “Kinetics and Stereochemistry of the Hydrolysis of Novel Chemical Nerve Agents by a Series of Phosphotriesterase Mutants”, Journal of Chemical and Biological Defense (accepted 2/10/15).
297. S. S. Kamat and F. M. Raushel, “PhnJ – A Novel Radical SAM Enzyme from the C-P Lyase Complex” Perspectives in Science, 4, 32-37 (2015).
296. A. Fedorov, R. M.-A., D. Hitchcock, V. V. Nemmara, E. V. Fedorov, S. C. Almo, and F. M. Raushel, “The Structure of N-Formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginonsa” Biochemistry 54, 890-897 (2015).
295. D. S. Hitchcock, A. A. Fedorov, E. V. Fedorov, S. C. Almo, and F. M. Raushel, “Discovery of a Bacterial 5-Methylcytosine Deaminase” Biochemistry 53, 7426-7435 (2014).
294. M. E. Hobbs, H. J. Williams, B. Hillerich, S. C. Almo, and F. M. Raushel, “L-Galactose Metabolism in Bacteroides vulgatus from the Human Gut Microbiota” Biochemistry 53, 4661-4670 (2014).
293. M. Korczynska, D. F. Xiang, Z. Zhang, C. Xu, T. Narindoshvili, S. Kamat, H. Williams, S. Chang, P. Kolb, B. Hillerich, J. Sauder, S. Burley, S. C. Almo, S. Swaminathan, B. Shoichet, F. M. Raushel, “Functional Annotation and Structural Characterization of a Novel Lactonase Hydrolyzing D-Xylono-1,4-Lactone-5-phosphate and L-Arabino-1,4-Lactone-5-phosphate” Biochemistry 53, 4727-4738 (2014).
292. K. Tipton, R. Armstrong, B. Bakker, A. Bairoch, A. Cornish-Bowden, P. J. Halling, J-H. Hofmeyr, T. S. Leyh, C. Kettner, F. M. Raushel, J. Rower, D. Schomburg, and C. Steinbeck, “Standards for Reporting Enzyme Data: The STRENDA Consortium: What it Aims to Do and Why it Should be Helpful” Perspectivesin Science, 1, 131-137 (2014).
291. D. F. Xiang, D. Kumaran, S. Swaminathan, and F. M. Raushel, “Structural Characterization and Function Determination of a Non-specific Carboxylate Esterase from the Amidohydrolase Superfamily with a Promiscuous Ability to Hydrolyze Methylphosphonate Esters” Biochemistry 53, 3476-3485 (2014). PMCID: PMC4045322
290. B. Manta, F. M. Raushel, and F. Himo, “Reaction Mechanism of Zinc-Dependent Cytosine Deaminase from Escherichia coli: A Quantum Chemical Study” Journal of Physical Chemistry B, 118, 5644-5652 (2014).
289. S. Barelier, J. A. Cummings, A. M. Goble, D. S. Hitchcock, J. Farelli, S. C. Almo, F. M. Raushel, K. N. Allen, and B. Shoichet, “Substrate Deconstruction and the Non-Additivity of Enzyme Recognition” Journal of the American Chemical Society, 136, 7374-7382 (2014).
288. J. A. Cummings, M. Vetting, S. V. Ghodge, C. Xu, B. Hillerich, R. D. Seidel, S. C. Almo, and F. M. Raushel, “Prospecting for Unannotated Enzymes: Discovery of a 3’,5’-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily” Biochemistry, 53, 591-600 (2014). PMCID: PMC3985815
287. D. Dunaway-Mariano, Hazel M. Holden and F. M. Raushel, “W. W. Cleland – A Catalytic Life” Biochemistry, 52, 9092-9096 (2013).
285. S. V. Ghodge, J. A. Cummings, H. J. Williams, and F. M. Raushel, “Discovery of a Cyclic Phosphodiesterase that Catalyzes the Sequential Hydrolysis of Both Ester Bonds to Phosphorus” Journal of the American Chemical Society, 135, 16360-16363 (2013). PMCID: PMC3864833.
284. S. S. Kamat, E. S. Burgos, and F. M. Raushel, “Potent Inhibition of the C-P Lyase Nucleosidase PhnI by ImmucillinA-Triphosphate” Biochemistry 52, 7366-7368 (2013). PMCID: PMC3838859.
283. A. M. Goble, Youjun Feng, F. M. Raushel, and John E. Cronan, “Discovery of a cAMP Deaminase that Quenches Cyclic AMP-Dependent Regulation” ACS Chemical Biology 8, 2622-2629 (2013). PCMID: PMC3838859
282. D. S. Hitchcock, H. Fan, J. Kim, M. Vetting, B.
Hillerich, R. D. Seidel, S. C. Almo, B. K. Shoichet, A.
Sali, and F. M. Raushel, “Structure-Guided
Enzymology: Discovery of New Deaminase Enzymes”
Journal of the American Chemical Society 135, 13927-13933
(2013). PMCID:
PMC3827683.
281. M. M. Meier, C. Rajendran, C. Malisi, M. Fox, C. Xu, S. Schlee, D. P. Barondeau, B. Höcker, R. Sterner, and F. M. Raushel, “Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template” Journal of the American Chemical Society, 135, 11670-11677 (2013). PMCID: PMC3786566.
280. A. M. Goble, R. Toro, X. Li, A. Ornelas, H. Fan, S. Eswaramoorthy, Y. Patskovsky, B. Hilerich, R. Seidel, A. Sali, S. C. Almo, S. Swaminathan, M. E. Tanner, and F. M. Raushel, “Deamination of 6-Aminodeoxyfutalosine in Menaquinone Biosynthesis by Distantly Related Enzymes,” Biochemistry 52, 6525-6536 (2013). PMCID: 3813303.
279. A. N. Bigley, C. Xu, T. J. Henderson, S. P. Harvey, and F. M. Raushel, “Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriestease for Phosphorothiolate Hydrolysis” Journal of the American Chemical Society, 135, 10426-10432 (2013). PMCID: 3747228.
278. S. S. Kamat and F. M. Raushel, “The Enzymatic Conversion of Phosphonates to Phosphate by Bacteria” Current Opinion in Chemical Biology, 17, 589-596 (2013).
277. S. S. Kamat, H. J. Williams, and F. M. Raushel, “Phosphonates to Phosphate: A Functional Annotation of the Essential Genes of the Phn Operon in Escherichia coli" Beilstein Institute, Experimental Standard Conditions of Enzyme Characterization, Carsten Kettner-editor, pp. 1-17 (2013).
276. S. S. Kamat, H. J. Williams, L. S. Dangott, M. Chakrabarti, and F. M. Raushel, “The Catalytic Mechanism for Aerobic Formation of Methane by Bacteria” Nature, 497, 132-136 (2013).
275. S. Ghodge, A. Fedorov, E. V. Fedorov, R. Seidel, B. Hillerich, S. C. Almo, “Structural and Mechanistic Characterization of L-Histidinol Phosphate Phosphatase from the PHP Family of Proteins” Biochemistry 52, 1101-1112 (2013). PMCID: PMC3570733.
274. H. Fan, D. Hitchcock, R. Seidel, B. Hillerich, H. Lin, A. Sali, S. Almo, B. Shoichet, and F. M. Raushel, “Assignment of Pterin Deaminase Activity to an Enzyme of Unknown Function Guided by Homology Modeling and Docking” Journal of the American Chemical Society 135, 795-803 (2013). PMCID: PMC3557803.
273. S. S. Kamat and F. M. Raushel, “Adenine Deaminase” Encyclopedia of Inorganic and Bioinorganic Chemistry” ed. R. A. Scott, John Wiley: Chichester. DOI 10.1002/9781119951438.eibc2172 (2013).
272. A. Bigley and F. M. Raushel, “Catalytic Mechanisms for Phosphotriesterases” Biochemica, Biophysica Acta 1843, 443-453 (2013). PMCID: PMC3421070
271. A. N. Bigley and F. M Raushel, “The Zinc Amidohydrolase Superfamily” in Encyclopedia of Metalloproteins (V. N. Uversky, R. H. Kretsinger, and E. A. Permyakov, eds.) Springer pp. 2354-2359 (2013).
270. M. E. Hobbs, M. Vetting, H. J. Williams, T. Narindoshvili, D. M. Kebodeaux, B. Hillerich, R. D. Seidel, S. C. Almo, and F. M. Raushel, “Discovery of an L-Fucono-1,5-Lactonase from cog3618 of the Amidohydrolase Superfamily” Biochemistry, 52, 239-253 (2013). PMCID: PMC3542637.
269. A. Ornelas, M. Korczynska, S. Ragumani, D. Kumaran, T. Narindoshvili, B. K. Shoichet, S. Swaminathan, and F. M. Raushel, “Functional Annotation and Three-Dimensional Structure of an Incorrectly Annotated Dihydroorotase from cog3964 in the Amidohydrolase Superfamily” Biochemistry 52, 228-238 (2013). PMCID: PMC3542638.
268. E. Ghanem and F. M. Raushel, (October, 2012) “Enzymes: The Active Site”, In Encyclopedia of Life Sciences John Wiley & Sons, Ltd: Chichester http://www.els.net/ [doi: 10.1002/9780470015902.a0000714.pub2].
267. P.-C. Tsai, N. Fox, A. N. Bigley, S. P. Harvey, D. P. Barondeau, and F. M. Raushel, “Enzymes for the Homeland Defense: Optimizing Phosphotriesterase for the Hydrolysis of Organophosphate Nerve Agents” Biochemistry 51, 6463-6475 (2012). PMCID: PMC3447986
266. F. Fan, H. J. Williams, J. G. Boyer, T. L. Graham, H. Zhao, R. Lehr, H. Qi, B. Schwartz, F. M. Raushel, and T. D. Meek, “On the Catalytic Mechanism of Human ATP Citrate Lyase” Biochemistry 51, 5198-5211 (2012).
265. M. E. Hobbs, V. Malashkevich, H. J. Williams, C. Xu, J. M. Sauder, S. K. Burley, S. C. Almo, and F. M. Raushel, “Structure and Catalytic Mechanism of LigI: Insight into the Amidohydrolase Enzymes of cog3618 and Lignin Degradation”, Biochemistry 51, 3497-3507 (2012). PMCID: PMC3416963
264. D. F. Xiang, P. Kolb, A. A. Fedorov, C. Xu, E. V. Fedorov, T. Narindoshvili, H. Williams, B. K. Shoichet, S. C. Almo, and F. M. Raushel, “Structure-Based Function Discovery of an Enzyme for the Hydrolysis of Phosphorylated Sugar Lactones” Biochemistry, 51, 1762-1773 (2012). PMCID: PMC3298459
263. S. S. Kamat, G. H. Hampton, D. F. Xiang, S. E. Tichy, T. Gheyi, X. Zheng, K. Bain, C. Groshong, M. Russell, S. Emtage, J. M. Sauder, S. K. Burley, P. A. Lindahl and F. M. Raushel, "The Catalase Activity of Diiron Adenine Deaminase" Protein Science, 20, 2080-2094 (2011).
262. J. A. Gerlt, K. N. Allen, S. C. Almo, R. N. Armstrong, P. C. Babbitt, J. E. Cronan, D. Dunaway-Mariano, H. J. Imker, M. P. Jacobson, W. Minor, C. Dale Poulter, F. M. Raushel, A. Sali, B. K. Shoichet, and J. V. Sweedler, “The Enzyme Function Initiative” Biochemistry, 50, 9950-9962 (2011). PMCID: PMC3238057
261. S. S. Kamat, H. J. Williams, and F. M. Raushel, “Intermediates in the Transformation of Phosphonates to Phosphate in Bacteria” Nature 480, 570-573 (2011). PMCID: PMC3245791
260. A. M. Goble, H. Fan, A. Sali, and F. M. Raushel, “The Discovery of a Cytokinin Deaminase” ACS Chemical Biology, 6, 1036-1040 (2011). PMCID: PMC3199332
259. A. M. Goble, Z. Zhang, J. M. Sauder, S. K. Burley, S. Swaminathan, and F. M. Raushel, “Pa0148 from Pseudomonas aeruginosa Catalyzes the Deaminaton of Adenine”, Biochemistry, 50, 6589-6597 (2011). PMCID: PMC3131671.
258. D. S. Hitchcock, A. A. Fedorov, E. V. Fedorov, L. Dangott, S. C. Almo, and F. M. Raushel, “Rescue of the Orphan Enzyme Isoguanine Deaminase”, Biochemistry 50, 5555-5557 (2011). PMCID: PMC3138507
257. R. S. Hall, A. A. Hall, C. Xu, E. V. Fedorov, S. C. Almo, and F. M. Raushel, “The Three-Dimensional Structure and Catalytic Mechanism of Cytosine Deaminase”, Biochemistry, 50, 5077-5085 (2011). PMCID: PMC3107989.
256. F. M. Raushel, “Catalytic Detoxification” Nature, 469, 310-311 (2011).
255. S. Kamat, H. Fan, J. M. Sauder, S. K. Burley, B. K. Shoichet, A. Sali, and F. M. Raushel, "Enzymatic Deamination of the Epigenetic Base N-6-Methyladenine" Journal of the American Chemical Society, 133, 2080-2083 (2011). PMCID: PMC3043370.
254. S. Kamat, A. Bararia, D. Kumaran, G. P. Holmes-Hampton, H. Fan, A. Sali, J. M. Sauder, S. K. Burley, P. A. Lindahl, S. Swaminathan, and F. M. Raushel, "Catalytic Mechanism and Three-Dimensional Structure of Adenine Deaminase" Biochemistry, 50, 1917-1927 (2011). PMCID: PMC3059353.
