253.  A. Bigley and F. M. Raushel, "Phosphotriesterase" in The Handbook of Metalloproteins  Volumes 4 & 5, edited by A. Messerschmidt. Chichester, UK: John Wiley & Sons, Ltd, pp 665-678 (2010).

252.  F. M. Raushel, "Functional Annotation of Orphan Enzymes within the Amidohydrolase Superfamily" Proceedings of the 4th International Symposium on Experimental Standard Conditions of Enzyme Characterization (Beilstein Institute, Carsten Kettner-editor) pp. 9-19 (2010).  

251.  M. E. Meyer, J. A. Gutierrez, F. M. Raushel, and N. G. J. Richards, "A Conserved Glutamate Controls the Commitment to Acyl-Adenylate Formation in Asparagine Synthetase" Biochemistry 49, 9391-9401 (2010). PMCID: PMC2975022.

250.  P.-C. Tsai, Y. Fan, J. Kim, L. Yang, S. C. Almo, Y. Q. Gao, and F. M. Raushel,  "Structural Determinants for the Stereoselective Hydrolysis of Chiral Substrates by Phosphotriesterase" Biochemistry 49, 7988-7997 (2010). PMCID PMC2945819.

249.  P.-C. Tsai, A. Bigley, Y. Li, E. Ghanem, C. L. Cadieus, S. A. Kasten, T. E. Reeves, D. M. Cerasoli, and F. M. Raushel, "Stereoselective Hydrolysis of Organophosphate Nerve Agents by the Bacterial Phosphotriesterase" Biochemistry 49, 7979-7987 (2010). PMCID: PMC2945820.

248.  D. F. Xiang, Y. Patskovsky, C. Xu, A. A. Fedorov, E. V. Fedorov, A. A. Sisco, J. M. Sauder, S. K. Burley, S. C. Almo, and F. M. Raushel, "Functional Identification and Structure Determination of Two Novel Prolidases from cog1228 in the Amidohydrolase Superfamily"  Biochemistry  49, 6791-6803 (2010). PMCID: PMC2914802.

247.  R. S. Hall, R. Agarwal, D. Hitchcock, J. M. Sauder, S. K. Burley, S. Swaminathan, and F. M. Raushel, "Discovery and Structure Determination of the Orphan Enzyme Isoxanthopterin Deaminase" Biochemistry 49, 4374-4382 (2010). PMCID: PMC2892419.

246.  L. Lund, Y. Fan, Q. Shao, Y. Q. Gao, and F. M. Raushel, "Carbamate Transport in Carbamoyl Phosphate Synthetase: A Theoretical and Experimental Investigation" Journal of the American Chemical Society 132, 3870-3878 (2010).  PMCID: PMC2847351.

 

245.  R. S. Hall, A. A. Fedorov, R. Marti-Arbona, E. V. Fedorov, P. Kolb, J. M. Sauder, S. K. Burley, B. K. Shoichet, S. C. Almo, and F. M. Raushel, "The Hunt for 8-Oxoguanine Deaminase" Journal of the American Chemical Society 132, 1762-1763 (2010).  PMCID: PMC2820149.

 

244.  J. A. Cummings, T. T. Nguyen, A. A. Fedorov, P. Kolb, C. Xu, E. V. Fedorov, B. K. Shoichet, D. P. Barondeau, S. C. Almo, and F. M. Raushel, "Structure, Mechanism, and Substrate Profile for Sco3058: The Closest Bacterial Homologue to Human Renal Dipeptidase" Biochemistry 49, 611-622 (2010).  PMCID: PMC2808448

243. T. T. Nguyen, A. A. Fedorov, L. Williams, Y. Li, L. V. Fedorov, C. Xu, S. C. Almo, F. M. Raushel, “The Mechanism of the Reaction Catalyzed by Uronate Isomerase Illustrates How an Isomerase May Have Evolved from a Hydrolase within the Amidohydrolase Superfamily” Biochemistry 48, 8879-8890 (2009).  PMCID: PMC2773443

 

242. Y. Fan, L. Lund, Q. Shao, Y.-Q. Gao and F. M. Raushel, “A Combined Theoretical and Experimental Study of the Ammonia Tunnel in Carbamoyl Phosphate Synthetase” Journal of the American Chemical Society 131, 10211-10219 (2009).  PMCID: PMC2748306

241. J. Cummings, A. A. Fedorov, C. Xu, S. Brown, L. V. Fedorov, P. C. Babbitt, S. C. Almo, and F. M. Raushel, “Annotating Enzymes of Uncertain Function: The Deacylation of D-Amino Acids by Members of the Amidohydrolase Superfamily” Biochemistry, 48, 6469-6481 (2009).  PMCID: PMC2748305

240. D. F. Xiang, C. Xu, D. Kumaran, A. C. Brown, J. M. Sauder, S. K. Burley, S. Swaminathan, and F. M. Raushel, “Functional Annotation of Two New Carboxypeptidases from the Amidohydrolase Superfamily of Enzymes” Biochemistry, 48, 4567-4576 (2009).  PMCID:  PMC2748308. 

239.  D. F. Xiang, Y. Patskovsky, C. Yu, A. J. Meyer, S. C. Almo, and F. M. Raushel, “Functional Identification of Incorrectly Annotated Prolidases from the Amidohydrolase Superfamily of Enzymes” Biochemistry 48, 3730-3742 (2009).  PMCID: PMC2683473.

238. U. Pieper, R. Chiang, J. J. Seffernick, S. D. Brown, M. E. Glasner, L. Kelly, N. Eswar, M. Sauder, S. K. Burley, S. Almo, J. A. Gerlt, F. M. Raushel, B. K. Shoichet, M. P. Jacobson, P. P. Babbitt, and A. Sali, “Target Selection and Annotation for the Structural Genomics of the Amidohydrolase and Enolase Superfamilies” Journal of Structural and Functional Genomics 10, 107-125 (2009). PMCID: PMC2693957.

237. D. F. Xiang, P. Kolb, M. M. Meier, L. V. Fedorov, A. A. Fedorov, R. Sterner, S. C. Almo, B. K. Shoichet, and F. M. Raushel, “Functional Annotation and Three-Dimensional Structure of Dr0930 from Deinococcus radiodurans: A Close Relative of Phosphotriesterase in the Amidohydrolase Superfamily” Biochemistry 48, 2237-2247 (2009).

236.  J. Kim, P.-C. Tsai, S.-L. Chen, F. Himo, S. Almo, and F. M. Raushel, “Structure of Diethyl Phosphate bound to the Binuclear Metal Center of Phosphotriesterase”, Biochemistry 47, 9497-9504 (2008). PMCID: PMC2725523

235.  R. Z. Liao, J. G. Yu, F. M. Raushel, and F. Himo, “Theoretical Investigation of the Reaction Mechanism of the Dinuclear Zinc Enzyme Dihydroorotase” Chemistry: A European Journal 14, 4287-4292 (2008).

234.  R. Tyagi, S. Eswaramoorthy, S. K. Burley, F. M. Raushel, S. Swaminathan, “A Common Catalytic Mechanism for Proteins of HutI Family” Biochemistry 47, 5608-5615 (2008).

233.  R. Sterner, R. Merkl, and F. M. Raushel, “Computational Design of Enzymes” Chemistry and Biology, 15, 421-423 (2008).

232.  L. Williams, F. Fan, J. S. Blanchard, and F. M. Raushel, “Positional Isotope Exchange Analysis of the Mycobacterium smegmatis Cysteine Ligase (MshC)” Biochemistry, 47, 4843-4850 (2008)

231.  Y. Fan, L. Yang, L. Lund, F. M. Raushel, and Y. Q. Gao, “The Mechanism for the Transport of Ammonia within Carbamoyl Phosphate Synthetase Determined by Molecular Dynamics Simulations” Biochemistry, 47, 2935-2944 (2008).

230.  T. T. Nguyen, S. Brown, A. A. Fedorov, E. V. Fedorov, P. C. Babbitt, S. C. Almo, and F. M. Raushel, “At the Periphery of the Amidohydrolase Superfamily: Bh0493 from Bacillus halodurans Catalyzes the Isomerization of D-Galacturonate to D-Tagaturonate” Biochemistry, 47, 1194-1206 (2008).

229. V. Fresquet, L. Williams, and F. M. Raushel,  "Partial Randomization of the Four Sequential Amidation Reactions Catalyzed by Cobyric Acid Synthetase by a Single Point Mutation” Biochemistry, 46, 13983-13993 (2007). PMCID: PMC2518967

228.  J. Hermann, R. Marti-Arbona, E. Fedorov, A. Fedorov, S. Almo, B. K. Shoichet, and F. M. Raushel, “Structure-Based Activity Prediction for an Enzyme of Unknown Function” Nature, 448, 775-779 (2007). PMCID: PMC2254328

227.  E. Ghanem, Y. Li, C. Xu, and F. M. Raushel, “Characterization of a Phosphodiesterase Capable of Hydrolyzing EA2192, the Most Toxic Degradation Product of the Nerve Agent VX” Biochemistry 46, 9032-9040 (2007).

226.  Y. Li and F. M. Raushel, “Differentiation of Chiral Phosphorus Enantiomers by 31P and 1H NMR Spectroscopy Using Modified Amino Acids as Chemical Solvating Agents” Tetrahedron: Asymmetry 18, 1391-1397 (2007). PMCID: PMC2084221

225. R. S. Hall, S. Brown, A. Fedorov, L. Fedorov, P. C. Babbitt, S. C. Almo, and F. M. Raushel, “Structural Diversity within the Mononuclear and Binuclear Active Sites of N-Acetyl-D-Glucosamine-6-PhosphateDeacetylase” Biochemistry 46, 7953-7962 (2007).

224. R. S. Hall, D. F. Xiang, C. Xu, and F. M. Raushel, “N-Acetyl-D-Glucosamine-6-Phosphate: Substrate Activation via a Single Divalent Metal Ion” Biochemistry 46, 7942-7952 (2007). PMCID: PMC2533526

223. E. Ghanem and F. M. Raushel, “Enzymes: The Active Site”, In Encyclopedia of Life Sciences John Wiley & Sons, Ltd: Chichester http://www.els.net/ (2007).

222. C. R. Samples, F. M. Raushel, and V. J. DeRose, “Activation of the Binuclear Metal Center through Formation of Phosphotriesterase-Inhibitor Complexes” Biochemistry 46, 3435-3442 (2007).

221. L. Williams, V. Fresquet, P. J. Santander, and F. M. Raushel, “The Multiple Amidation Reactions Catalyzed by Cobyric Acid Synthetase from Salmonella typhimurium are Sequential and Dissociative” Journal of American Chemical Society 129, 294-295 (2007).

 

220.  G. Roteasa, Y. R. Tahboub, S. Dalijasevic, F. M. Raushel, and H. M. Abu-Soud, "Kinetic Evidence Supports the Existence of Two Halide Binding Sites that Display Distinct Impact on the Heme Iron Microenvironment in Myeloperoxidase" Biochemistry 46, 398-405 (2007).

219.  C. Nowlan, Y. Li, T. Evans, J. Carpenter, E. Ghanem, J. C. Hermann, B. K. Shoichet, and F. M. Raushel, “Resolution of Chiral Phosphate, Phosphonate, and Phosphinate Esters by an Enantioselective Enzyme Library” Journal of the American Chemical Society 128, 15892-15902, (2006).

218.  J. C. Hermann, E. Ghanem, Y. Li, F. M. Raushel, J. J. Irwin, and B. K. Shoichet, “Predicting Substrates by Docking High-Energy Intermediates to Enzyme Structures” Journal of the American Chemical Society 128, 15882-15891 (2006).

217.  R. Marti-Arbona and F. M. Raushel, “Mechanistic Characterization of N-Formimino-L-Glutamate Iminohydrolase from Pseudomonas aeruginosa” Biochemistry 45, 14256-14262 (2006).

216.  A. Weeks, L. Lund, and F. M. Raushel, “Tunneling of Intermediates in Enzyme-Catalyzed Reactions” Current Opinion in Chemical Biology 10, 465-472 (2006).

215.  L. Williams, T. Nguyen, Y. Li, T. N. Porter, and F. M. Raushel, “Uronate Isomerase: A Nonhydrolytic Member of the Amidohydrolase Superfamily with an Ambivalent Requirement for a Divalent Metal Ion” Biochemistry 45, 7453-7462 (2006). PMCID: PMC2505117

214.  Sakai, W. S. Yew, L. Song, D. F. Xiang, C. Xu, F. M. Raushel and J. A. Gerlt, “Evolution of Enzymatic Activities in the Enolase Superfamily:  N-Succinylamino Acid Racemase and a New Pathway for the Irreversible Conversion of D- to L-Amino Acids” Biochemistry 45, 4455-4462 (2006).

 

213.  C. Xu, R. Hall, J. Cummings, and F. M. Raushel, “Tight Binding Inhibitors of N-Acyl Amino Sugar and Amino Acid Deacetylases” Journal of the American Chemical Society 128, 4244-4255 (2006).

212.  Y. I. Korpan, F. M. Raushel, A. A. Nazarenko, A. P. Soldatkin, N. Jaffrezic-Renault, C. Martelet, “Sensitivity and Specificity Improvement of ISFET-based Biosensor for Potato Glycolalkaloids Detection” Journal of Agricultural and Food Chemistry 54, 707-712 (2006).

211. R. Marti-Arbona, C. Xu, S. Steele, A. Weeks, G. F. Kuty, C. M. Seibert, and F. M. Raushel, “Annotating Enzymes of Unknown Function: N-Formimino-L-Glutamate Deiminase is a Member of the Amidohydrolase Superfamily” Biochemistry 45, 1997-2005 (2006).