210.  R. Marti-Arbona, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Functional Significance of Glu-77 and Tyr-137 within the Active Site of Isoaspartyl Dipeptidase” Bioorganic Chemistry 33, 448-458 (2005).

209.  Y. Li and F. M. Raushel, “Inhibitors Designed for the Active Site of Dihydroorotase” Bioorganic Chemistry 33, 470-483 (2005).

208.  J. J. Irwin, F. M. Raushel, and B. K. Shoichet, “Virtual Screening Against Metalloenzymes for Inhibitors and Substrates” Biochemistry 44, 12316-12328 (2005).

207.  E. Ghanem and F. M. Raushel “Detoxification of Organophosphate Nerve Agents by Bacterial Phosphotriesterase” Toxicology and Applied Pharmacology 207, 5459-5470 (2005).

206. C. R. Samples, T. Howard, F. M. Raushel and V. J. DeRose, “Protonation of the Binuclear Metal Center within the Active Site of Phosphotriesterase” Biochemistry 44, 11005-11013 (2005).

205.  S. P. Harvey, J. E. Kolakowski, T.-C. Cheng,Vipin K. Rastogi, L. P. Reiff, J. J. DeFrank, F. M. Raushel, and C. Hill, “Stereoselectivity in the Enzymatic Hydrolysis of Cyclosarin (GF)” Enzyme and Microbial Technology  37, 547-555 (2005).

204.  R. Marti-Arbona, V. Fresquet, J. B. Thoden, M. L. Davis, H. M. Holden and F. M. Raushel, “Mechanism of the Reaction Catalyzed by Isoaspartyl Dipeptidase from Escherichia coli” Biochemistry 44, 7115-7124 (2005).

203.  C. M. Seibert and F. M. Raushel “Structural and Catalytic Diversity within the Amidohydrolase Superfamily” Biochemistry  44, 6383-6391 (2005).

202.  G. E. Lawson, Y. W. Lee, F. M. Raushel and A. Singh, “Phospholipid-based Catalytic Nanocapsules” Advanced Functional Materials 15, 267-272 (2005).

201.  T. N. Porter, Y. Li, and F. M. Raushel “Mechanism of the Dihydroorotase Reaction” Biochemistry 43, 16285-16292 (2004).

200.  H. M. Abu-Soud, F. M. Raushel, and S. L. Hazen, “A Novel Multistep Mechanism for Oxygen Binding to Ferrous Hemoproteins: Rapid Kinetic Analysis of Ferrous-Dioxy Myeloperoxidase (Compound III) Formation” Biochemistry 43, 11589-11595 (2004).

199.  J. B. Thoden, X. Huang, J. Kim, F. M. Raushel, and H. M. Holden, “Long Range Allosteric Transitions in Carbamoyl Phosphate Synthetase” Protein Science 13, 2398-2405 (2004). PMCID: PMC2280008

198.  V. Fresquet, L. Williams, and F. M. Raushel, “Mechanism of Cobyrinic Acid a,c-Diamide Synthetase from Salmonella typhimurium LT2” Biochemistry 43, 10619-10627 (2004).        

197. M. Park, C. M. Hill, Y. Li, R. K. Hardy, H. Khanna, Y. Khang and F. M. Raushel “Catalytic Properties of the PepQ Prolidase from Escherichia coli” Archives of Biochemistry & Biophysics 429, 224-230 (2004).

196. Y. Li, S. D. Aubert, E. G. Maes, and F. M. Raushel, “Enzymatic Resolution of Chiral Phosphinate Esters” Journal of American Chemical Society 126, 8888-8889 (2004).

195.  S. D. Aubert, Y. Li, and F. M. Raushel, “Mechanism for the Hydrolysis of Organophosphates by the Bacterial Phosphotriesterase” Biochemistry 43, 5707-5715 (2004).

194.  J. Kim and F. M. Raushel, “Perforation of the Tunnel Wall in Carbamoyl Phosphate Synthetase Derails the Passage of Ammonia between Sequential Active Sites” Biochemistry 43, 5334-5340 (2004).

193.  S.-H. Hong and F. M. Raushel, “Control of Stereoselectivity in Phosphotriesterase” Methodsin Enzymology 388, 256-266 (2004).

192.  J. Kim and F. M. Raushel, “Access to the Carbamate Tunnel of Carbamoyl Phosphate Synthetase” Archives of Biochemistry & Biophysics 425, 33-41 (2004).

191.  V. Fresquet, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Kinetic Mechanism of Asparagine Synthetase from Vibrio cholerae” Bioorganic Chemistry 32, 63-75 (2004).

190.  F. M. Raushel, “Kinetic Evolution to the Catalytic Core of the Bacterial Phosphotriesterase” in Enzyme Functionality: Design, Engineering and Screening (Allan Svendsen, ed. Marcel Dekker, Inc.) pp. 247-259 (2003).

189.  J. B. Garrett, L. S. Mullins, and F. M. Raushel, “Effect of Linker Sequence on the Stability of Circularly Permuted Variants of Ribonuclease T1” Bioorganic Chemistry 31, 412-424 (2003).

188.  K. T. Lum, H. J. Huebner, Y. Li, T. D. Phillips, and F. M. Raushel, “Organophosphate Nerve Agent Toxicity in Hydra attenuata”  Chemical Research in Toxicology 16, 953-957 (2003).

187.  C. M. Hill, W.-S. Li, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Enhanced Degradation of Chemical Warfare Agents through Molecular Engineering of the Phosphotriesterase Active Site” Journal of American Chemical Society 125, 8990-8991 (2003).

186.  F. M. Raushel, J. B. Thoden, and H. M. Holden, “Enzymes with Molecular Tunnels” Accounts in Chemical Research 36, 539-548 (2003).

185.  Y. Li, S. D. Aubert, and F. M. Raushel, “Operational Control of Stereoselectivity During the Enzymatic Hydrolysis of Racemic Organophosphorus Compounds” Journal of American Chemical Society 125, 7526-7527 (2003).

184.  J. B. Thoden, J. Kim, F. M. Raushel, and H. M. Holden, “The Catalytic Mechanism of Galactose Mutarotase” Protein Science 12, 1051-1059 (2003). PMCID: PMC2323875

183.  J. B. Thoden, R. Marti-Arbona, F. M. Raushel, and H. M. Holden “High Resolution X-ray Structure of Isoaspartyl Dipeptidase from Escherichia coli” Biochemistry 42, 4874-4882 (2003).

182.  L. Williams, R. Zheng, J. S. Blanchard, and F. M. Raushel, “A Positional Isotope Exchange Analysis of the Pantothenate Synthetase Reaction” Biochemistry 42, 5108-5113 (2003).

181.  J. A. Gerlt and F. M. Raushel, “Evolution of Function in (β/α)8-Barrel Enzymes” Current Opinion in Chemical Biology 7, 252-264 (2003).

180.  J. B. Thoden, J. Kim, F. M. Raushel, and H. M. Holden, "Structural and Kinetic Studies of Sugar Binding to Galactose Mutarotase from Lactococcus lactis” Journal of Biological Chemistry 277, 45458-45465 (2002).

179.  J. Thoden, X. Huang, F. M. Raushel, and H. M. Holden, “Carbamoyl Phosphate Synthetase: Creation of an Escape Route for Ammonia” Journal of Biological Chemistry 277, 39722-39727 (2002).

178.  J. Kim, S. Howell, X. Huang, and F. M. Raushel, “Structural Defects within the Carbamate Tunnel of Carbamoyl Phosphate Synthetase” Biochemistry 41, 12575-12581 (2002).

177.   F. M. Raushel, “Bacterial Detoxification of Organophosphate Nerve Agents” Current Opinion in Microbiology 5, 288-295 (2002).

176.  W. Li, Y. Li, C. M. Hill, K. T. Lum, and F. M. Raushel, “Enzymatic Synthesis of Chiral Organophosphothioates from Prochiral Precursors” Journal of American Chemical Society 124, 3498-3499 (2002).

175.  O. Pierrat, F. Javid-Majd and F. M. Raushel, “Dissection of the Conduit for Allosteric Control of Carbamoyl Phosphate Synthetase by Ornithine” Archives of Biochemistry & Biophysics 400, 26-33 (2002).

174.  O. Pierrat and F. M. Raushel, “A Functional Analysis of the Allosteric Nucleotide Monophosphate binding Site of Carbamoyl Phosphate Synthetase” Archives of Biochemistry & Biophysics 400, 34-42 (2002).

173.  B. W. Miles, J. B. Thoden, H. M. Holden, and F. M. Raushel, “Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin”, Journal of Biological Chemistry 277, 4368-4373 (2002).

172.  M. A. Anderson, H. Shim, F. M. Raushel, and W. W. Cleland, “Hydrolysis of Phosphotriesters: Determination of Transition States in Parallel Reactions by Heavy-Atom Isotope Effects” Journal of American Chemical Society 123, 9246-9253 (2001).

171.  J. Kim and F. M. Raushel, “Allosteric Control of the Oligomerization of Carbamoyl Phosphate Synthetase from Escherichia coli” Biochemistry 40, 11030-11036 (2001).

170.  W.-S. Li, K. T. Lum, M. Chen-Goodspeed, M. A. Sogorb, and F. M. Raushel, “Stereoselective Detoxification of Chiral Sarin and Soman Analogs by Phosphotriesterase”  Bioorganic & Medicinal Chemistry 9, 2083-2091 (2001).

169.  J. B. Thoden, G. N. Phillips, T. M. Neal, F. M. Raushel, H. M. Holden, “Molecular Structure of Dihydroorotase: A Paradigm for Catalysis Through the Use of a Binuclear Metal Center” Biochemistry 40, 6989-6997 (2001).

168.  X. Huang, H. M. Holden, and F. M. Raushel, “Channeling of Substrates and Intermediates in Enzyme Catalyzed Reactions” Annual Reviews of Biochemistry 70, 149-180 (2001).

167.  C. M. Hill, W.-S. Li, T.-C. Cheng, J. J. DeFrank, and F. M. Raushel, “Stereochemical Specificity of Organophosphorus Acid Anhydrolase Toward p-Nitrophenyl Analogs of Soman and Sarin" Bioorganic Chemistry 29, 27-35 (2001).

166.  M. M. Benning, H. Shim, F. M. Raushel, and H. M. Holden, “High Resolution X-ray Structures of Different Metal-Substituted Forms of Phosphotriesterase from Pseudomonas diminuta” Biochemistry 40, 2712-2722 (2001).

165. M. Chen-Goodspeed, M. A. Sogorb, F. Wu, and F. M. Raushel, “Enhancement, Relaxation, and Reversal of the Stereoselectivity for Phosphotriesterase by Rational Evolution of Active Site Residues” Biochemistry 40, 1332-1339 (2001).

164.  M. Chen-Goodspeed, M. A. Sogorb, F. Wu, S.-B. Hong, and F. M. Raushel, “Structural Determinants of the Substrate and Stereochemical Specificity of Phosphotriesterase” Biochemistry 40, 1325-1331 (2001).