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Our publications are organized by:
The Labile Ni Site of ACS“Discovery of a Labile Ni Ion Required for CO/Acetyl-CoA Exchange Activity in the NiFe Complex of CO Dehydrogenase from Clostridium thermoaceticum.” W. Shin and P.A. Lindahl. J. Am. Chem. Soc. 114, 9718 (1992). “Heterogeneous Nickel Environments in Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum.” W. Shin, M.E. Anderson and P.A. Lindahl. J. Am Chem. Soc. 115, 5522 (1993). A-Cluster Properties“Methylation of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum and the Mechanism of Acetyl-CoA Synthesis” David P. Barondeau and Paul A. Lindahl J. Am. Chem. Soc. 1997, 119, 3959 - 3970. Get pdf “Spectroscopic, Redox and Structural Characterization of the Ni-Labile and Nonlabile Forms of the Acetyl-CoA Synthase Active Site of Carbon Monoxide Dehydrogenase” William K. Russell, Christina M. V. Stålhandske, Jinqiang Xia, Robert A. Scott, and Paul A. Lindahl, J. Am. Chem. Soc. 1998, 120, 7502-7510. Get pdf “Equilibrium Dialysis Study and Mechanistic Implications of Coenzyme A Binding to Acetyl-CoA Synthase/Carbon Monoxide Dehydrogenase from Moorella thermoaceticum” Bruce E. Wilson and Paul A. Lindahl, Journal of Biological Inorganic Chemistry, 1999, 4, 742-748.
Alpha Subunit Studies"Assembly of an Exchange-Coupled [Ni:Fe4S4] Cluster in the a Metallosubunit of CO Dehydrogenase from Clostridium thermoaceticum with Spectroscopic Properties and CO-Binding Ability Mimicking the Acetyl-CoA Synthase Active Site" Jinqiang Xia and Paul A. Lindahl. J. Am. Chem. Soc. 1996, 118, 483-484. Get pdf “Mössbauer and EPR Study of the Ni-Activated a Subunit of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum“ Jinqiang Xia, Zhengguo Hu, Codrina Popescu, Paul A. Lindahl, and Eckard Münck. J. Am. Chem. Soc. 1997, 119, 8301 - 8312. Get pdf "Genetic Construction of Truncated and Chimeric Metalloproteins Derived from the Alpha Subunit of Acetyl-CoA Synthase from Clostridium Thermoaceticum", Huay-Keng Loke, Xiangshi Tan, and Paul A. Lindahl, Journal of the American Chemical Society, 2002, 124, 8667-8772. "Reduction and Methyl Transfer Kinetics of the Alpha Subunit from Acetyl-Coenzyme A Synthase", Xiangshi Tan, Christopher Sewell, Qingwu Yang, and Paul A. Lindahl, Journal of the American Chemical Society, 2003, 125, 318-319. B- and C-Cluster Properties“Identification of a Cyanide Binding Site of CO Dehydrogenase from Clostridium thermoaceticum using EPR and ENDOR Spectroscopies.” M.E. Anderson, V.J. DeRose, B.M. Hoffman and P.A. Lindahl. J. Am. Chem. Soc. 115, 12204 (1993). “Organization of clusters and Internal Electron Pathways in CO Dehydrogenase from Clostridium thermoaceticum: Relevance to Mechanism of Catalysis and CN- Inhibition.” M.E. Anderson and P.A. Lindahl. Biochemistry. 33, 8702 (1994). "Spectroscopic States of the CO Oxidation / CO2 Reduction Active Site of Carbon Monoxide Dehydrogenase and Mechanistic Implications" Mark E. Anderson and Paul A. Lindahl Biochemistry. 1996, 35, 8371-8380. Get pdf "Nature of the C-Cluster in Ni-Containing Carbon Monoxide Dehydrogenases", Zhengguo Hu, Nathan J. Spangler, Mark E. Anderson, Jinqiang Xia, Paul W. Ludden, Paul A. Lindahl, and Eckard Münck*, Journal of the American Chemical Society; 1996; 118(4); 830-845. Get pdf "ENDOR of the C-cluster of CO Dehydrogenase from Clostridium thermoaceticum: Evidence for Histidine, Cysteine, and Hydroxyl Coordination to the Fe4S4 Moiety" Victoria J. DeRose, Mark E. Anderson, Paul A. Lindahl, and Brian M. Hoffman J. Am. Chem. Soc. 1998, 120, 8767-8776. Get pdf Redox Titrations of ACS"Spectroelectrochemical Characterization of the Metal Centers in Carbon Monoxide Dehydrogenase (CODH) and Nickel-deficient CODH from Rhodospirillum rubrum" Nathan J. Spangler, Paul A. Lindahl, Vahe Bandarian, and Paul W. Ludden J. Biol. Chem. 1996 271: 7973-7977. Get pdf “CO/CO2 Potentiometric Titrations of Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum: Effect of CO2 and Evidence for Redox Cooperativity” William K. Russell and Paul A. Lindahl Biochemistry, 1998, 37, 10016-10026. Get pdf “Stoichiometric CO Reductive Titrations of Acetyl-CoA Synthase (Carbon Monoxide Dehydrogenase) from Clostridium thermoaceticum” Daniel M. Fraser and Paul A. Lindahl, Biochemistry 1999, 38, 15697-15705. Get pdf “Evidence for a Proposed Intermediate Redox State in the CO/CO2 Active Site of Acetyl-Coenzyme A Synthase (Carbon Monoxide Dehydrogenase) from Clostridium thermoaceticum” Daniel M. Fraser and Paul A. Lindahl, Biochemistry 1999, 38, 15706-15711. Get pdf "Stoichiometric Redox Titrations of Complex Metalloenzymes", Paul A. Lindahl, Method Enzymol., 2002, 354, 296-309. Kinetic Studies of ACS“Evidence of a Molecular Tunnel Connecting the Active Sites for CO2 Reduction and Acetyl-CoA Synthesis in Acetyl-CoA Synthase from Clostridium thermoaceticum” Ernest L. Maynard and Paul A. Lindahl, Journal of the American Chemical Society, 1999, 121 9221-9222. Get pdf “Kinetic Mechanism of Acetyl-CoA Synthase: Steady-State Synthesis at Variable CO/CO2 Pressures” Ernest L. Maynard, Chris Sewell and Paul A. Lindahl, Journal of the American Chemical Society, 2001 ASAP article. Get pdf "Catalytic coupling of the active sites in Acetyl-CoA synthase, a bifunctional CO-Channeling enzyme" Ernest L. Maynard and Paul A. Lindahl, Biochemistry, 2001, 40, 13262-13267. "Stopped-flow Kinetics of Methyl Group Transfer Between the Corrinoid-Iron-Sulfur Protein and Acetyl-Coenzyme A Synthase from Clostridium Thermoaceticum" Xiangshi Tan, Christopher Sewell, and Paul A. Lindahl, Journal of the American Chemical Society, 2002, 124, 6277-6284. "Reduction and Methyl Transfer Kinetics of the Alpha Subunit from Acetyl-Coenzyme A Synthase", Xiangshi Tan, Christopher Sewell, Qingwu Yang, and Paul A. Lindahl, Journal of the American Chemical Society, 2003, 125, 318-319. Recombinant ACS“Active Acetyl-CoA Synthase from Clostridium thermoaceticum obtained by Cloning and Heterologous Expression of acsAB in Escherichia coli”, Huay-Keng Loke, George N. Bennett, and Paul A. Lindahl, Proc. Natl. Acad. Sci. USA, 2000, 97, 12530-12535. Get pdf "Genetic Construction of Truncated and Chimeric Metalloproteins Derived from the Alpha Subunit of Acetyl-CoA Synthase from Clostridium Thermoaceticum", Huay-Keng Loke, Xiangshi Tan, and Paul A. Lindahl, Journal of the American Chemical Society, 2002, 124, 8667-8772.
The Evolution of ACS“The Evolution of Acetyl-CoA Synthase” Paul A. Lindahl and Belinda Chang, Origins Life Evol. B, 2001, 4, 403-434. “Stepwise
Evolution of Nonliving to Living Chemical Systems” Paul A. Lindahl, Origins
of Life and Evolution of the Biosphere, 2003,
in press. Redox Titrations of Hydrogenase“Stability of the Ni-C State and Oxidative Titrations of Desulfovibrio gigas Hydrogenase Monitored by EPR and Electronic Absorption Spectroscopies.” D.P. Barondeau, L.M. Roberts and P.A. Lindahl. J. Am Chem. Soc. 116, 3442 (1994). “Analysis of Oxidative Titrations of Desulfovibrio gigas Hydrogenase; Implications for the Catalytic Mechanism.” L.M. Roberts and P.A. Lindahl. Biochemistry. 33, 14339 (1994). Other“2,4,6-Trinitrotoluene (TNT) Reduction by Carbon Monoxide Dehydrogenase from Clostridium thermoaceticum” Shouqin Huang, Paul A. Lindahl, Chuanyue Wang, George N. Bennett, Fredrick B. Rudolf, and Joseph B. Hughes, Applied and Environmental Microbiology 2000 66, 1474-1478. "Stoichiometric Redox Titrations of Complex Metalloenzymes", Paul A. Lindahl, Method Enzymol., 2002, 354, 296-309. "The Ni-Containing Carbon Monoxide Dehydrogenase Family: Light at the End of the Tunnel?" Paul A. Lindahl, Biochemistry, 2002, 41, 2097-2105. "Identification and Preliminary Characterization of acsF, a Putative Ni-Insertase Used in the Biosynthesis of Acetyl-CoA Synthase from Clostridium thermoaceticum", Huay-Keng Loke and Paul A. Lindahl, Journal of Inorganic Biochemistry, 2003, in press.
Computational Biology Studies"Analysis of Protein Homeostatic Regulatory Mechanisms in Perturbed Environments at Steady State", Christopher Sewell, Jeffrey J. Morgan, and Paul A. Lindahl, J. Theor. Biol., 2002, 215, 151-167. “Dynamic Responses of Protein Homeostatic Regulatory Mechanisms to Perturbations from Steady State”, Qingwu Yang, Paul A. Lindahl and Jeffrey J. Morgan, Journal of Theoretical Biology, 2003, in press.
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