CHAPTER 11

Reactions of Alkyl Halides

Learning Objectives: Learn the mechanisms used to describe the various reactions of alkyl halides. Be able to describe the effect of solvent, substrate structure, and nucleophile/base have on the mechanism and the outcome of the reaction. Be able to predict the most-likely mechanism for the reactions of alkyl halides.

 

Reading for Nov. 5 - thru Section 11.9

 

Chapter Problems:

 

SN2 Mechanism: 11.1 - 11.3, 11.25

 

SN1 Mechanism: 11.8, 11.11, 11.44, 11.45

 

Predict the product: 11.4, 11.14, 11.23, 11.26, 11.29, 11.37 - 11.40

 

Effects of solvent, substrate, nucleophile:

SN2: 11.5 - 11.7, 11.18, 11.19, 11.22, 11.24, 11.28, 11.30, 11.41

SN1: 11.10, 11.12, 11.13, 11.20, 11.27, 11.30

 

Elimination Reactions: 11.15, 11.16

 

Predict the mechanism: 11.17

 

Synthesis: 11.21, 11.31 - 11.33, 11.35, 11.55