Organic ChemistryThe areas of organic synthesis, new organic reactions, organometallic reactions, and bioorganic and biological chemistry are strongly represented in the research projects of the chemistry faculty at Texas A&M. Other research areas include marcomolecular and polymer chemistry, catalysis, and natural products.
The combination of instrumentation available through the Department and individual research groups is among the best in the country for organic and bioorganic research. Several high field multinuclear NMR spectrometers, mass spectrometers, and x-ray diffractometers are available for access. A variety of molecular graphics systems are routinely used by students.
Barondeau, David P
Associate Professor of Chemistry. B. A., 1989, Southern Utah State College. Ph.D. 1996, Texas A&M University. La Jolla Interfaces in Sciences Fellow 1997-1998; NIH Postdoctoral Fellow, 1998-2000; Senior Research Associate, 2002-2006, The Scripps Research Institute. Biological Chemistry. Bioinorganic chemistry, metal cofactor biosynthesis, post-translational modification chemistry, enzyme catalysis, protein crystallography.
Begley, Tadhg P
Professor of Chemistry, B.S. National University of Ireland, 1977, California Institute of Technology, 1983. Biological, Organic, and Bioorganic chemistry. Mechanistic chemistry and enzymology of complex organic transformations, particularly those found on the vitamin biosynthetic pathways.
Bergbreiter, David E
Professor of Chemistry. B. S., 1970, Michigan State University. Ph. D., 1974, Massachusetts Institute of Technology. Organic Chemistry. Reactions at polymeric surfaces; polymers in heterogeneous catalysis; polymer chemistry; transition metal catalysis; polymer synthesis; asymmetric organic synthesis; organometallic chemistry.
Rachal Professor of Chemistry. B. S., 1979, University of Bath. M. S., 1980, University of East Anglia. Ph. D., 1983, Cambridge University. Postdoctoral Fellow, 1984, University of Wisconsin. Research Fellow, 1985-87, Cambridge University. Organic synthesis and biomedicinal chemistry. Design and synthesis of small molecules to perturb protein-protein interaction. Targeting tumors and healthy cells using molecules designed to interact with cell surface receptors for imaging and chemotherapeutic applications. Dyes for intracellular imaging. Asymmetric catalysis and peptidomimetic chemistry.
Gabbai, Francois P
Davidson Professor in Science and Professor of Chemistry. Ph. D., 1994, University of Texas at Austin. Alexander von Humboldt Postdoctoral Fellow, 1994-1996, and European Community Research Fellow (Habilitation), 1996-1998, Technical University of Munich. Organometallic/Inorganic Main Group Chemistry. Polyfunctional Lewis Acids in Molecular Recognition. Catalysis and Supramolecular Materials.
Gladysz, John A
Dow Chair in Chemical Invention and Distinguished Professor of Chemistry
B. S. , 1971, University of Michigan and Ph. D. 1974, Stanford University. Organic Chemistry/Organometallic Chemistry/Catalysis. Organic synthesis including enantioselective reactions and mechanistic studies, molecular devices, materials chemistry, and green chemistry.
Harding, Kenn E
Professor of Chemistry. B. S., 1964, Oklahoma State University. Ph.D., 1968, Stanford University. NIH Postdoctoral Fellow, 1968-69, Harvard University. Program Director, 1985-86, National Science Foundation. Organic Chemistry. Natural Products synthesis, stereoselectivity of cyclofunctionalization reactions; stereoselective synthesis of cyclic and acyclic polyfunctional amines; enantioselective synthesis.
Associate Professor of Chemistry. B.S., 2000, Beijing University. Ph.D., 2005, University of California-Davis. Postdoctoral Fellow, 2005-2007, the Scripps Research Institute. Biological Chemistry. Protein-protein/DNA interaction network in living cells; Structures and functions of selenoproteins; Protein modification; Peptide library screening.
Ozerov, Oleg V
Professor of Chemistry. Ph. D., 2000, University of Kentucky. Postdoctoral associate, 2000-2002, Indiana University. Organometallic chemistry and catalytic applications of main group and transition elements. Carbon-fluorine bond activation. Chemistry and energy.
Raushel, Frank M
Distinguished Professor of Chemistry and Davidson Professor of Science. B. A., 1972, St. Thomas College. Ph. D., 1976, University of Wisconsin Madison. Postdoctoral Fellow, 1976-80, Pennsylvania State University. Biochemistry. Determination of enzyme reaction mechanisms and protein structure using kinetic, genetic, and magnetic resonance techniques.
Professor of Chemistry. B. A., 1986, Texas A&M University. Ph. D., 1991, Colorado State University. American Cancer Society Postdoctoral Fellow, 1991-93, Harvard University. Organic Chemistry. Structure elucidation, total synthesis, and mode of actions studies of physiologically active natural products; synthetic methodology including asymmetric catalysis.
Singleton, Daniel A
Davidson Professor of Science and Professor of Chemistry. B. S., 1980, Case Western Reserve University. Ph.D., 1986, University of Minnesota. NIH Postdoctoral Fellow, 1986-87, University of Wisconsin at Madison. Organic Chemistry. Organic synthetic methodology; cycloadditions reactions; intramolecular cyclizations; isotope effects.
Watanabe, Coran M H
Associate Professor of Chemistry. B.S., 1992, University of Hawaii. Ph.D., 1998, The Johns Hopkins University. Howard Hughes Postdoctoral Fellow of the Life Sciences Foundation, 2002, The Scripps Research Institute. Bio-organic chemistry. Bio-engineering of natural product biosynthetic pathways. Cell-based screening, mRNA expression profiling (on a genome-wide scale), and structure elucidation of natural products.
Wheeler, Steven E
Assistant Professor of Chemistry. B. A., 2002, New College of Florida. Ph. D., 2006, University of Georgia. NIH Postdoctoral Fellow 2006-2010, University of California, Los Angeles. Computational/Physical/Organic Chemistry. Non-covalent interactions, organocatalysis, computational thermochemistry.
Wooley, Karen L
W. T. Doherty-Welch Chair and Distinguished Professor of Chemistry. B.S., 1988, Oregon State University. Ph.D., 1993, Cornell University. Organic/Polymer/Materials Chemistry. Organic and polymer synthesis; novel macromolecular nanostructures for biomedical and materials applications; degradable polymers; nanoscale polymer assemblies; functional polymers; polymer modification.
Assistant Professor of Chemistry. B.S. 1994, M.S. 1997, Lanzhou University. M.S. 1999, New York University. Ph.D. 2003, Ohio State University. Postdoctoral Scholar, 2003-2004, The Scripps Research Institute. National Institutes of Health Kirschstein-NRSA Postdoctoral Fellow, 2005-2007, Harvard University and Broad Institute of Harvard & MIT. Organic Chemistry. Total synthesis of bioactive natural products. Development of new synthetic methods. Identification of small molecule probes for biological studies.