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Contacting CBI

Dr. Burgess


http://www.chem.tamu.edu/rgroup/burgess/main.html
burgess@tamu.edu

I worked with Professor A. R Katrizky (MSc; University of East Anglia), Lord Lewis (PhD; Cambridge University) and Professor B. M. Trost (postdoctoral, U. Wisconsin).  After, I spent two years in Cambridge, UK, funded by a fellowship to promote independent research, then moved to Rice University as an assistant professor.  In 1992, I joined to Texas A & M where I am now a called Rachal Professor of Chemistry.

Our group focuses on synthesis and synthetic methodology to tackle problems of relevance to medicinal chemistry and biotechnology.  Essentially, the three current active projects are:

  • syntheses, mediated by organometallic catalysts, of privileged chirons found in natural products;
  • syntheses of dipeptide mimics;
  • use of a special method to construct combinatorial libraries of molecules designed to disrupt or mimic protein-protein interactions; and,
  • syntheses of fluorescent through-bond-energy-transfer cassettes to facilitate observation of protein-protein interactions in cells.